SCHEMBL16169703

SCHEMBL16169703

CC(=N)NCCCOc1cc(OCCCNC(=N)N)cc(-c2ccc3sc4ccc(-c5cc(OCCCN)c(OCCCN)c(OCCCN)c5)cc4c3c2)c1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ PIM1 P11309 1/20 0.33
▸ PIM2 Q9P1W9 1/20 0.33
▸ CSF3R Q99062 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16169701 0.94 CSF3R (0.36) PIM1PIM2CSF3R
SCHEMBL16169705 0.92 F9 (0.32) —
SCHEMBL16169694 0.90 F9 (0.34) PIM1PIM2CSF3R
SCHEMBL16172090 0.87 F9 (0.33) —
SCHEMBL15805867 0.84 F9 (0.36) —
SCHEMBL15805960 0.83 PIM1 (0.39) PIM1PIM2CSF3R
SCHEMBL16169699 0.81 PIM1 (0.40) PIM1PIM2CSF3R
SCHEMBL15805864 0.76 PIM1 (0.43) PIM1PIM2CSF3R
SCHEMBL16169700 0.75 PIM1 (0.39) PIM1PIM2
SCHEMBL16419736 0.75 L3MBTL1 (0.40) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140308317-A1 Polymeric Compounds And Methods Of Making And Using The Same CELLCEUTIX CORPORATION (US) 2014-10-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140308317-A1 Polymeric Compounds And Methods Of Making And Using The Same ALG1, CD44, MUC1 PIM1 1725/4885PIM2 2729/4885CSF3R 1989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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