SCHEMBL16170338

SCHEMBL16170338

C=CC(=O)Sc1ccc(-c2ccc(SC(=O)C=C)c(C)c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.33
RXRB P28702 4/20 0.31
RARB P10826 1/20 0.31
RXRA P19793 3/20 0.31
RXRG P48443 1/20 0.30
BRD4 O60885 1/20 0.30
BRD9 Q9H8M2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16170479 1.00 MCL1 (0.33) MCL1RXRBRARBRXRARXRG
SCHEMBL16170373 0.89
SCHEMBL16170480 0.89
SCHEMBL16170428 0.89
SCHEMBL16170496 0.89
SCHEMBL16170577 0.85 HSD17B1 (0.39) MCL1RXRBRARBRXRA
SCHEMBL23051185 0.83 HPGD (0.36) MCL1RXRBRARBRXRARXRG
SCHEMBL16170502 0.82 TTR (0.38) RARB
SCHEMBL16170547 0.82 KDM4E (0.37) RARB
SCHEMBL16170433 0.82 KDM4E (0.37) RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9382353-B2 Polymerizable compound having thioester group, polymerizable composition and liquid crystal display device JNC CORPORATION (JP) 2016-07-05 US disclosed
US-9382353-B2 Polymerizable compound having thioester group, polymerizable composition and liquid crystal display device JNC CORPORATION (JP) 2016-07-05 US disclosed
US-20140306157-A1 POLYMERIZABLE COMPOUND HAVING THIOESTER GROUP, POLYMERIZABLE COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-10-16 US disclosed
US-20140306157-A1 POLYMERIZABLE COMPOUND HAVING THIOESTER GROUP, POLYMERIZABLE COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-10-16 US disclosed