SCHEMBL16171984

SCHEMBL16171984

COCCCCCCOCOc1ccc(/C=C/C(=O)c2ccccc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.63
MAPT P10636 1/20 0.63
RAB9A P51151 1/20 0.63
KMT2A Q03164 1/20 0.63
BCHE P06276 13/20 0.60
CYP3A4 P08684 1/20 0.60
NFKB1 P19838 1/20 0.60
NFKB2 Q00653 1/20 0.60
RELA Q04206 1/20 0.60
ACHE P22303 11/20 0.60
MAOB P27338 2/20 0.56
MAOA P21397 1/20 0.56
PPARA Q07869 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16171985 0.91 MAPT (0.67) NPC1MAPTRAB9AKMT2ABCHE
SCHEMBL12062070 0.89 NPC1 (0.64) NPC1MAPTRAB9AKMT2ABCHE
SCHEMBL12062066 0.87 NPC1 (0.62) NPC1MAPTRAB9AKMT2ABCHE
SCHEMBL13223567 0.86 MAPT (0.74) NPC1MAPTRAB9AKMT2ABCHE
SCHEMBL12062063 0.85 BCHE (0.62) NPC1MAPTRAB9AKMT2ABCHE
SCHEMBL15501514 0.84 BCHE (0.58) NPC1MAPTRAB9AKMT2ABCHE
SCHEMBL12062058 0.84 BCHE (0.58) NPC1MAPTRAB9AKMT2ABCHE
SCHEMBL25238725 0.83 XDH (0.65) NPC1MAPTRAB9AKMT2AMAOB
SCHEMBL28749420 0.83 NPC1 (0.69) NPC1MAPTRAB9AKMT2ABCHE
SCHEMBL27578079 0.83 NPC1 (0.69) NPC1MAPTRAB9AKMT2ABCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9465244-B2 Liquid crystal display SONY CORPORATION (JP) 2016-10-11 US disclosed
US-20140307211-A1 LIQUID CRYSTAL DISPLAY SONY CORPORATION (JP) 2014-10-16 US disclosed