Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.35 |
| ▸ | PDE6D | O43924 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23181275 | 0.89 | SMN1; SMN2 (0.49) | HPGDHTTSMN1; SMN2PDE6DHDAC3 | |
| SCHEMBL14870351 | 0.85 | HTT (0.46) | HPGDHTTSMN1; SMN2PDE6DHDAC3 | |
| SCHEMBL15146938 | 0.85 | SMN1; SMN2 (0.46) | HPGDHTTSMN1; SMN2PDE6DHDAC3 | |
| SCHEMBL13225533 | 0.83 | SMN1; SMN2 (0.49) | HPGDHTTSMN1; SMN2PDE6DHDAC3 | |
| SCHEMBL16870946 | 0.83 | SMN1; SMN2 (0.42) | HPGDHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL19343049 | 0.83 | SMN1; SMN2 (0.42) | HPGDHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL24686923 | 0.82 | SMN1; SMN2 (0.62) | HPGDHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL14115871 | 0.82 | MEN1 (0.34) | HPGDHTTSMN1; SMN2HDAC3HDAC4 | |
| SCHEMBL22969982 | 0.82 | SMN1; SMN2 (0.42) | HPGDHTTSMN1; SMN2PDE6DHDAC3 | |
| SCHEMBL22710221 | 0.80 | HPGD (0.45) | HPGDHTTSMN1; SMN2PDE6DHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140309175-A1 | POLYMERIC CONJUGATES OF C1-INHIBITORS | BELROSE PHARMA INC (US) | 2014-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140309175-A1 | POLYMERIC CONJUGATES OF C1-INHIBITORS | SERPINC1, C1S, C1R | HPGD 981/4885HTT 2206/4885SMN1; SMN2 3911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.