Glutarate

Glutarate

SCHEMBL16174471

O=C([O-])CCCC(=O)O.O=C([O-])CCCC(=O)O.O=C([O-])CCCC(=O)O.O=C([O-])CCCC(=O)O.[Hf+4]

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.65
LMNA P02545 4/20 0.56
TSHR P16473 3/20 0.53
NFKB1 P19838 2/20 0.53
PMP22 Q01453 1/20 0.53
CA1 P00915 1/20 0.48
CAMK2A Q9UQM7 1/20 0.48
GABRR3 A8MPY1 1/20 0.46
GABRP O00591 1/20 0.46
GABRD O14764 1/20 0.46
HDAC3 O15379 1/20 0.46
GABBR2 O75899 1/20 0.46
CYP1A2 P05177 1/20 0.46
THRB P10828 1/20 0.46
GABRA1 P14867 1/20 0.46
GABRB1 P18505 1/20 0.46
GABRG2 P18507 1/20 0.46
GABRR1 P24046 1/20 0.46
GABRB3 P28472 1/20 0.46
GABRR2 P28476 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutarate SCHEMBL107714 0.94 SLC22A6 (0.65) SLC22A6LMNATSHRNFKB1PMP22
Glutarate SCHEMBL106178 0.94 SLC22A6 (0.65) SLC22A6LMNATSHRNFKB1PMP22
Glutarate SCHEMBL106585 0.94 SLC22A6 (0.65) SLC22A6LMNATSHRNFKB1PMP22
Glutarate SCHEMBL30592618 0.94 SLC22A6 (0.65) SLC22A6LMNATSHRNFKB1PMP22
Glutarate SCHEMBL31216427 0.94 SLC22A6 (0.65) SLC22A6LMNATSHRNFKB1PMP22
Glutarate SCHEMBL9930402 0.92 SLC22A6 (0.61) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL105952 0.88 LMNA (0.65) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL105192 0.88 LMNA (0.65) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL21489542 0.88 LMNA (0.65) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL30776749 0.88 LMNA (0.65) SLC22A6LMNATSHRNFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9178096-B2 Luminescent solar concentrator LEIDOS, INC. (US) 2015-11-03 US disclosed
US-20150287864-A1 Luminescent Solar Concentrator LEIDOS, INC. 2015-10-08 US disclosed
US-8866001-B1 Luminescent solar concentrator LEIDOS, INC. (US) 2014-10-21 US disclosed