Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9803597 | 0.99 | NPC1 (0.46) | NPC1RAB9ATP53MAPTALDH1A1 | |
| SCHEMBL9558103 | 0.91 | ALDH1A1 (0.45) | NPC1RAB9ATP53MAPTALDH1A1 | |
| SCHEMBL9558112 | 0.91 | ALDH1A1 (0.45) | NPC1RAB9ATP53MAPTALDH1A1 | |
| SCHEMBL1618209 | 0.90 | ALDH1A1 (0.43) | NPC1RAB9ATP53MAPTALDH1A1 | |
| SCHEMBL1617727 | 0.89 | ALDH1A1 (0.43) | NPC1RAB9ATP53MAPTALDH1A1 | |
| SCHEMBL1617907 | 0.86 | MAPT (0.40) | NPC1RAB9ATP53MAPTALDH1A1 | |
| SCHEMBL1617957 | 0.85 | MAPT (0.39) | NPC1RAB9ATP53MAPTALDH1A1 | |
| SCHEMBL1618083 | 0.83 | RAB9A (0.40) | NPC1RAB9ATP53MAPTALDH1A1 | |
| SCHEMBL1618574 | 0.82 | MAPT (0.46) | MAPTALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL9557823 | 0.82 | RAB9A (0.37) | NPC1RAB9ATP53MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58157779-A | — | — | None | — | — | JP | disclosed |
| US-7923488-B2 | Leuco dyes with a N,N-dialkylamino, N,N-diarylamino, N-alkyl-N-arylamino, N-alkylamino, or N-arylamino group on one of the aromatic rings and a latent curing agent or catalyst activate-able by heat, pressure, or radiation | TRILLION SCIENCE, INC. (US) | 2011-04-12 | — | — | US | disclosed |
| US-20080090943-A1 | Leuco dyes with a N,N-dialkylamino, N,N-diarylamino, N-alkyl-N-arylamino, N-alkylamino, or N-arylamino group on one of the aromatic rings and a latent curing agent or catalyst activate-able by heat, pressure, or radiation | TRILLION, INC. | 2008-04-17 | — | — | US | disclosed |
| EP-0232907-B1 | HEAT-SENSITIVE RECORDING MATERIAL | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1991-03-27 | — | — | EP | disclosed |
| EP-0188377-B1 | NEW PHTHALIDE DERIVATIVES | KANZAKI PAPER MANUFACTURING CO., LTD (JP) | 1988-11-09 | — | — | EP | disclosed |
| US-4761396-A | BASIC PHTHALIDE DYE REACTS WITH FLUORENE DERIVATIVE AND P-PHENYLENEDIAMINE DERIVATIVE | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1988-08-02 | — | — | US | disclosed |
| US-4748148-A | Recording system utilizing phthalide derivatives as colorless chromogenic material | NEW OJI PAPER CO., LTD. (JP) | 1988-05-31 | — | — | US | disclosed |
| US-4730057-A | Phthalide derivatives useful as colorless chromogenic material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1988-03-08 | — | — | US | disclosed |
| US-4704379-A | Pressure sensitive manifold sheet | KANZAKI PAPER MANUFACTURING CO. LTD. (JP) | 1987-11-03 | — | — | US | disclosed |
| EP-0062544-B1 | NEW PHTHALIDE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND RECORDING SYSTEM UTILIZING THE SAME AS COLOURLESS CHROMOGENIC MATERIAL | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1987-09-30 | — | — | EP | disclosed |
| US-4641160-A | Recording system utilizing phthalide derivatives as colorless chromogenic material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1987-02-03 | — | — | US | disclosed |
| EP-0196484-A1 | Pressure sensitive manifold sheet | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1986-10-08 | — | — | EP | disclosed |
| EP-0188377-A1 | New phthalide derivatives | KANZAKI PAPER MANUFACTURING CO., LTD (JP) | 1986-07-23 | — | — | EP | disclosed |
| US-4580153-A | COLOR FORMING BETWEEN COLORLESS CHROMOGENIC VINYL PHTHALIDE COMPOUND AND ELECTRON ACCEPTOR | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1986-04-01 | — | — | US | disclosed |
| JP-S58157779-A | PHTHALIDE DERIVATIVE, ITS PREPARATION, AND RECORDING MATERIAL USING IT | KANZAKI PAPER MFG CO LTD | 1983-09-19 | — | — | JP | disclosed |
| EP-0062544-A1 | New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1982-10-13 | — | — | EP | disclosed |