Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2221711 | 0.89 | MAPT (0.42) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL19124186 | 0.89 | MAPT (0.42) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL16115326 | 0.89 | MAPT (0.42) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL16393888 | 0.83 | AAK1 (0.41) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL16393678 | 0.83 | AAK1 (0.41) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL4652737 | 0.78 | MAPT (0.54) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL6989260 | 0.76 | ALDH1A1 (0.38) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL2700060 | 0.76 | ALDH1A1 (0.48) | MAPTALDH1A1KMT2AHCAR3SMN1; SMN2 | |
| SCHEMBL20958028 | 0.76 | ALDH1A1 (0.48) | MAPTALDH1A1KMT2AHCAR3SMN1; SMN2 | |
| SCHEMBL932480 | 0.75 | ALDH1A1 (0.44) | MAPTALDH1A1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383888-B9 | NEW PEPTIDES HAVING ANTIMICROBIAL ACTIVITY AND NEW ENZYME CAPABLE OF CONVERTING L-CONFIGURED RESIDUE IN D-CONFIGURED AMINO ACID IN A PEPTIDE | INSTITUT NATIONAL DE RECH POUR LAGRICULTURE LALIMENTATION ET LENVIRONNEMENT (FR) | 2023-10-04 | — | — | EP | disclosed |
| EP-3383888-B1 | NEW PEPTIDES HAVING ANTIMICROBIAL ACTIVITY AND NEW ENZYME CAPABLE OF CONVERTING L-CONFIGURED RESIDUE IN D-CONFIGURED AMINO ACID IN A PEPTIDE | INSTITUT NATIONAL DE RECH POUR LAGRICULTURE LALIMENTATION ET LENVIRONNEMENT (FR) | 2023-06-07 | — | — | EP | disclosed |
| US-10981957-B2 | Peptides having antimicrobial activity and new enzyme capable of converting L-configured residue in D-configured amino acid in a peptide | INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (FR) | 2021-04-20 | — | — | US | disclosed |
| US-20180346526-A1 | NEW PEPTIDES HAVING ANTIMICROBIAL ACTIVITY AND NEW ENZYME CAPABLE OF CONVERTING L-CONFIGURED RESIDUE IN D-CONFIGURED AMINO ACID IN A PEPTIDE | INSTITUTE NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA) (FR) | 2018-12-06 | — | — | US | disclosed |
| WO-2014170295-A1 | COMPOUNDS POTENTIATING THE ACTIVITY OF ANTIFUNGAL DRUGS | FUNDACIÓN MEDINA. CENTRO DE EXCELENCIA EN INVESTIGACIÓN DE MEDICAMENTOS INNOVADORES EN ANDALUCÍA (ES) | 2014-10-23 | — | — | WO | disclosed |
| EP-2792683-A1 | Compounds potentiating the activity of antifungal drugs | Fundacion MEDINA. Centro de Excelencia en Investigacion de Medicamentos Innovadores en Andalucia (ES) | 2014-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10981957-B2 | Peptides having antimicrobial activity and new enzyme capable of converting L-configured residue in D-configured amino acid in a peptide | PEPD, DNPEP, ANPEP | MAPT 4876/4885GAA 255/4885ALDH1A1 1722/4885 |
| US-20180346526-A1 | NEW PEPTIDES HAVING ANTIMICROBIAL ACTIVITY AND NEW ENZYME CAPABLE OF CONVERTING L-CONFIGURED RESIDUE IN D-CONFIGURED AMINO ACID IN A PEPTIDE | DNPEP, PEPD, ANPEP | MAPT 4877/4885GAA 299/4885ALDH1A1 1916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.