Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | AADAC | P22760 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989256 | 0.77 | ALDH1A1 (0.46) | ALDH1A1ARHTTCES2ABCB11 | |
| SCHEMBL16174698 | 0.76 | MAPT (0.40) | ALDH1A1ARHTTCES2ABCB11 | |
| SCHEMBL8407371 | 0.73 | ALDH1A1 (0.50) | ALDH1A1ARHTTCES2ABCB11 | |
| SCHEMBL26097943 | 0.70 | ALDH1A1 (0.57) | ALDH1A1HTTLMNACYP1A2CYP3A4 | |
| SCHEMBL26097939 | 0.70 | ALDH1A1 (0.57) | ALDH1A1HTTLMNACYP1A2CYP3A4 | |
| SCHEMBL5579250 | 0.68 | ALDH1A1 (0.40) | ALDH1A1ARHTTCES2ABCB11 | |
| SCHEMBL5303809 | 0.68 | KMT2A (0.57) | ALDH1A1HTTLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL27676029 | 0.68 | KMT2A (0.57) | ALDH1A1HTTLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL1637175 | 0.66 | MAPT (0.52) | ALDH1A1HTTLMNACYP2C9CYP2C19 | |
| SCHEMBL8895665 | 0.66 | KMT2A (0.51) | ALDH1A1HTTLMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307193-A1 | AGONISTS OF FOLLICLE STIMULATING HORMONE ACTIVITY | Affymax Research Institute (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002009706-A1 | AGONISTS OF FOLLICLE STIMULATING HORMONE ACTIVITY | SMITHKLINE BEECHAM CORPORATION (US) | 2002-02-07 | — | — | WO | disclosed |