Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 7/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 7/20 | 1.00 |
| ▸ | F3 | P13726 | 3/20 | 1.00 |
| ▸ | PNLIP | P16233 | 1/20 | 1.00 |
| ▸ | NOS2 | P35228 | 1/20 | 1.00 |
| ▸ | CES1 | P23141 | 4/20 | 0.76 |
| ▸ | CES2 | O00748 | 2/20 | 0.76 |
| ▸ | RELA | Q04206 | 3/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.72 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.71 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.71 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.71 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.71 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.71 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.71 |
| ▸ | PTPRC | P08575 | 2/20 | 0.71 |
| ▸ | PTPRF | P10586 | 2/20 | 0.71 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.71 |
| ▸ | ACP1 | P24666 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oleanonic Acid SCHEMBL12200334 | 1.00 | PTPN2 (1.00) | PTPN2PTPN1F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL12313105 | 1.00 | PTPN2 (1.00) | PTPN2PTPN1F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL18687844 | 1.00 | PTPN2 (1.00) | PTPN2PTPN1F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL18688313 | 1.00 | PTPN2 (1.00) | PTPN2PTPN1F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL246220 | 1.00 | PTPN2 (1.00) | PTPN2PTPN1F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL12337276 | 1.00 | PTPN2 (1.00) | PTPN2PTPN1F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL2762433 | 1.00 | PTPN2 (1.00) | PTPN2PTPN1F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL6898284 | 1.00 | PTPN2 (1.00) | PTPN2PTPN1F3PNLIPNOS2 | |
| SCHEMBL17166004 | 0.92 | PTPN1 (0.85) | PTPN2PTPN1F3PNLIPNOS2 | |
| SCHEMBL16152971 | 0.89 | PTPN1 (0.81) | PTPN2PTPN1F3PNLIPNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576586-B1 | C-28 AMIDES OF MODIFIED C-3 BETULINIC ACID DERIVATIVES AS HIV MATURATION INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-08-12 | — | — | EP | disclosed |
| EP-2712863-B1 | Novel inhibitors of bacterial biofilms and related methods | SEQUOIA SCIENCES INC (US) | 2014-10-22 | — | — | EP | disclosed |