Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.81 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.81 |
| ▸ | F3 | P13726 | 1/20 | 0.81 |
| ▸ | PNLIP | P16233 | 1/20 | 0.81 |
| ▸ | NOS2 | P35228 | 1/20 | 0.81 |
| ▸ | CES2 | O00748 | 2/20 | 0.72 |
| ▸ | CES1 | P23141 | 2/20 | 0.72 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.65 |
| ▸ | STAT3 | P40763 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.63 |
| ▸ | RELA | Q04206 | 1/20 | 0.63 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.63 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.63 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.63 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30278367 | 1.00 | PTPN1 (0.81) | PTPN1PTPN2F3PNLIPNOS2 | |
| SCHEMBL18687848 | 1.00 | PTPN1 (0.81) | PTPN1PTPN2F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL18688313 | 0.89 | PTPN2 (1.00) | PTPN1PTPN2F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL2762433 | 0.89 | PTPN2 (1.00) | PTPN1PTPN2F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL12337276 | 0.89 | PTPN2 (1.00) | PTPN1PTPN2F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL6898284 | 0.89 | PTPN2 (1.00) | PTPN1PTPN2F3PNLIPNOS2 | |
| SCHEMBL17166004 | 0.89 | PTPN1 (0.85) | PTPN1PTPN2F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL18687844 | 0.89 | PTPN2 (1.00) | PTPN1PTPN2F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL12200334 | 0.89 | PTPN2 (1.00) | PTPN1PTPN2F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL12313105 | 0.89 | PTPN2 (1.00) | PTPN1PTPN2F3PNLIPNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2786757-B1 | 2-SUBSTITUTED OLEANOLIC ACID DERIVATIVE, METHOD PREPARING FOR SAME, AND APPLICATION THEREOF | HANGZHOU BENSHENG PHARMACEUTICAL CO LTD (CN) | 2017-08-16 | — | — | EP | disclosed |
| US-9156801-B2 | 2-substituted oleanolic acid derivative, method preparing for same, and application thereof | HANGZHOU BENSHENG PHARMACEUTICAL CO., LTD. (CN) | 2015-10-13 | — | — | US | disclosed |
| US-9156801-B2 | 2-substituted oleanolic acid derivative, method preparing for same, and application thereof | HANGZHOU BENSHENG PHARMACEUTICAL CO., LTD. (CN) | 2015-10-13 | — | — | US | disclosed |
| US-20140343064-A1 | 2-SUBSTITUTED OLEANOLIC ACID DERIVATIVE, METHOD PREPARING FOR SAME, AND APPLICATION THEREOF | Hanghzhou Bensheng Pharmaceutical Co., Ltd (CN) | 2014-11-20 | — | — | US | disclosed |
| US-20140343064-A1 | 2-SUBSTITUTED OLEANOLIC ACID DERIVATIVE, METHOD PREPARING FOR SAME, AND APPLICATION THEREOF | Hanghzhou Bensheng Pharmaceutical Co., Ltd (CN) | 2014-11-20 | — | — | US | disclosed |
| EP-2786757-A1 | 2-SUBSTITUTED OLEANOLIC ACID DERIVATIVE, METHOD PREPARING FOR SAME, AND APPLICATION THEREOF | Hangzhou Bensheng Pharmaceutical Co., Ltd. (CN) | 2014-10-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343064-A1 | 2-SUBSTITUTED OLEANOLIC ACID DERIVATIVE, METHOD PREPARING FOR SAME, AND APPLICATION THEREOF | CYP27A1, SOAT2, OSBP2 | PTPN1 4010/4885PTPN2 2908/4885F3 1853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.