SCHEMBL1617685

SCHEMBL1617685

COCCCC1=C(C)C(=O)NC1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.39
ALDH1A1 P00352 4/20 0.35
MAPT P10636 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
THRB P10828 1/20 0.35
PTPN2 P17706 1/20 0.34
PTPN1 P18031 1/20 0.34
CDC25B P30305 1/20 0.34
LMNA P02545 1/20 0.34
PGR P06401 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
MAOA P21397 1/20 0.34
TBXA2R P21731 1/20 0.34
MAPK1 P28482 1/20 0.34
AVPR2 P30518 1/20 0.34
CYP2C19 P33261 1/20 0.34
HTR2B P41595 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8443084 0.81 MAPT (0.40) ALDH1A1MAPTTDP1THRBPTPN2
SCHEMBL2579044 0.81 MAPT (0.40) ALDH1A1MAPTTDP1THRBPTPN2
SCHEMBL8442749 0.81 MAPT (0.40) ALDH1A1MAPTTDP1THRBPTPN2
SCHEMBL8443621 0.81 MAPT (0.40) ALDH1A1MAPTTDP1THRBPTPN2
SCHEMBL8443626 0.79 PTPN2 (0.35) PTPN2PTPN1CDC25B
SCHEMBL1535486 0.78 ALDH1A1 (0.42) DAOALDH1A1MAPTTDP1THRB
SCHEMBL1535496 0.76 ALDH1A1 (0.49) ALDH1A1MAPTTDP1THRBCDC25B
SCHEMBL5970520 0.74 ALDH1A1 (0.51) ALDH1A1MAPTTDP1THRBCDC25B
SCHEMBL8438882 0.74 ALDH1A1 (0.51) ALDH1A1MAPTTDP1THRBCDC25B
SCHEMBL5722122 0.74 ALDH1A1 (0.51) ALDH1A1MAPTTDP1THRBCDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020122947-A1 Coating composition comprising a reactive diluent AKZO NOBEL N.V. (NL) 2002-09-05 US claimed
WO-2002034843-A1 COATING COMPOSITION COMPRISING A REACTIVE DILUENT AKZO NOBEL N.V. (NL) 2002-05-02 WO claimed
EP-1963392-B2 MULTILAYER COATING SYSTEM AKZO NOBEL COATINGS INT BV (NL) 2012-08-01 EP disclosed
CN-101331165-B Multilayer coating system AKZO NOBEL COATINGS INT BV 2011-11-16 CN disclosed
US-7923113-B2 Shorter drying times; clear coats; addition of a basic catalyst; isocyanate-functional compound and thiol-functional compound; useful in repair and refinish of automobiles AKZO NOBEL COATING INTERNATIONAL B.V. (NL) 2011-04-12 US disclosed
EP-1963392-B1 MULTILAYER COATING SYSTEM AKZO NOBEL COATINGS INT BV (NL) 2009-08-05 EP disclosed
US-20090142600-A1 MULTILAYER COATING SYSTEM AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2009-06-04 US disclosed
CN-101331165-A Multilayer coating system AKZO NOBEL COATINGS INT BV (NL) 2008-12-24 CN disclosed
EP-1963392-A1 MULTILAYER COATING SYSTEM Akzo Nobel Coatings International BV (NL) 2008-09-03 EP disclosed
US-20070202341-A1 Multilayer Coating System AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2007-08-30 US disclosed
WO-2007068683-A1 MULTILAYER COATING SYSTEM AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2007-06-21 WO disclosed
CN-1416442-A Compsns. Comprosing isocyanate-functional compound, and isocyanate-reacthve compound, and co-catalyst AKZO NOBEL NV (NL) 2003-05-07 CN disclosed
EP-1263828-A1 COMPOSITIONS COMPRISING AN ISOCYANATE-FUNCTIONAL COMPOUND, AND ISOCYANATE-REACTIVE COMPOUND, AND A CO-CATALYST Akzo Nobel N.V. (NL) 2002-12-11 EP disclosed
US-20020122947-A1 Coating composition comprising a reactive diluent AKZO NOBEL N.V. (NL) 2002-09-05 US disclosed
CN-1349547-A Composition comprising mercapto-functional compounds AKZO NOBEL NV (NL) 2002-05-15 CN disclosed
WO-2002034843-A1 COATING COMPOSITION COMPRISING A REACTIVE DILUENT AKZO NOBEL N.V. (NL) 2002-05-02 WO disclosed
EP-1177232-A1 COMPOSITION COMPRISING MERCAPTO-FUNCTIONAL COMPOUNDS Akzo Nobel N.V. (NL) 2002-02-06 EP disclosed
US-20010047071-A1 Compositions comprising an isocyanate-functional compound, an isocyanate-reactive compound, and a co-catalyst AKZO NOBEL N.V. (NL) 2001-11-29 US disclosed
WO-2001068736-A1 COMPOSITIONS COMPRISING AN ISOCYANATE-FUNCTIONAL COMPOUND, AND ISOCYANATE-REACTIVE COMPOUND, AND A CO-CATALYST AKZO NOBEL N.V. (NL) 2001-09-20 WO disclosed
WO-2000064959-A1 COMPOSITION COMPRISING MERCAPTO-FUNCTIONAL COMPOUNDS AKZO NOBEL N.V. (NL) 2000-11-02 WO disclosed