Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8712391 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL3677355 | 0.86 | — | — | |
| Bromide SCHEMBL7929219 | 0.83 | HTR2A (0.30) | — | |
| Fluoride Ion SCHEMBL22228303 | 0.83 | — | — | |
| Iodide SCHEMBL7933888 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL7184244 | 0.77 | BRD4 (0.35) | — | |
| Hydrochloric Acid SCHEMBL5695982 | 0.77 | BRD4 (0.37) | — | |
| Hydrochloric Acid SCHEMBL137960 | 0.77 | HTR2A (0.39) | — | |
| Hydrochloric Acid SCHEMBL29424565 | 0.77 | HTR2A (0.39) | — | |
| Hydrochloric Acid SCHEMBL28189655 | 0.76 | BRD4 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7923401-B2 | Single-site catalyst activators, processes for making same, and use thereof in catalysts and polymerization of olefins | ALBERMARLE CORPORATION (US) | 2011-04-12 | — | — | US | disclosed |
| US-20090247398-A1 | SINGLE-SITE CATALYST ACTIVATORS, PROCESSES FOR MAKING SAME, AND USE THEREOF IN CATALYSTS AND POLYMERIZATION OF OLEFINS | ALBEMARLE CORPORATION (US) | 2009-10-01 | — | — | US | disclosed |