Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL7933888 | 0.97 | — | — | |
| Bromide SCHEMBL7929219 | 0.97 | HTR2A (0.30) | — | |
| Fluoride Ion SCHEMBL22228303 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL1617754 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL3674444 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL29773582 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL29773584 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL8712391 | 0.76 | — | — | |
| Bromide SCHEMBL29773605 | 0.75 | HTR2A (0.33) | — | |
| Iodide SCHEMBL29773491 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982236-B2 | Process to polymerize olefins | UNIVATION TECHNOLOGIES, LLC (US) | 2006-01-03 | — | — | US | claimed |
| EP-0705851-B9 | Catalyst systems and process for producing broad molecular weight distribution polyolefin | CONOCOPHILLIPS CO (US) | 2004-08-11 | — | — | EP | claimed |
| US-20040039138-A1 | Catalyst preparation method | WENZEL TIMOTHY T (US) | 2004-02-26 | — | — | US | claimed |
| EP-0705851-B1 | Catalyst systems and process for producing broad molecular weight distribution polyolefin | CONOCOPHILLIPS CO (US) | 2004-01-21 | — | — | EP | claimed |
| US-6656866-B2 | Metallocene and non-metallocene, homogeneous catalysts, particularly for use in the economical gas and slurry phase processes; spray dried olefin polymerization catalysts | UNIVATION TECHNOLOGIES, LLC | 2003-12-02 | — | — | US | claimed |
| US-20030207762-A9 | CATALYST PREPARATION METHOD | UNIVATION TECHNOLOGIES, LLC | 2003-11-06 | — | — | US | claimed |
| US-20020119890-A1 | Catalyst preparation method | WENZEL TIMOTHY T (US) | 2002-08-29 | — | — | US | claimed |
| EP-0685485-B1 | High activity ethylene selective metallocenes | PHILLIPS PETROLEUM CO (US) | 2000-08-16 | — | — | EP | claimed |
| US-5534473-A | METALLOCENES AND COCATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1996-07-09 | — | — | US | claimed |
| EP-0705851-A2 | Catalyst systems and process for producing broad molecular weight distribution polyolefin | PHILLIPS PETROLEUM COMPANY (US) | 1996-04-10 | — | — | EP | claimed |
| EP-0685485-A1 | High activity ethylene selective metallocenes | PHILLIPS PETROLEUM COMPANY (US) | 1995-12-06 | — | — | EP | claimed |
| EP-4345115-A2 | POLYOLEFIN RESIN PREPARED USING HETEROGENEOUS CATALYST AND METHOD OF PREPARING SAME | DL Chemical Co., Ltd. (KR) | 2024-04-03 | — | — | EP | disclosed |
| US-11332553-B2 | Catalyst composition for polymerizing polyolefin, method for producing polyolefin, and polyolefin resin | DL CHEMICAL CO., LTD. (KR) | 2022-05-17 | — | — | US | disclosed |
| EP-3686223-A2 | CATALYST COMPOSITION FOR POLYMERIZING POLYOLEFIN, METHOD FOR PRODUCING POLYOLEFIN, AND POLYOLEFIN RESIN | Daelim Industrial Co., Ltd. (KR) | 2020-07-29 | — | — | EP | disclosed |
| US-20200231717-A1 | CATALYST COMPOSITION FOR POLYMERIZING POLYOLEFIN, METHOD FOR PRODUCING POLYOLEFIN, AND POLYOLEFIN RESIN | DL CHEMICAL CO., LTD. (KR) | 2020-07-23 | — | — | US | disclosed |
| EP-0946610-A1 | HIGH ACTIVITY METALLOCENE POLYMERIZATION PROCESS | EXXON CHEMICAL PATENTS INC. (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028350-A1 | HIGH ACTIVITY METALLOCENE POLYMERIZATION PROCESS | EXXON CHEMICAL PATENTS INC. (US) | 1998-07-02 | — | — | WO | disclosed |
| US-5594078-A | BRIDGED FLUORENYL METALLOCENE CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| US-5534473-A | METALLOCENES AND COCATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0705851-A2 | Catalyst systems and process for producing broad molecular weight distribution polyolefin | PHILLIPS PETROLEUM COMPANY (US) | 1996-04-10 | — | — | EP | disclosed |