Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.54 |
| ▸ | ITGAV | P06756 | 11/20 | 0.54 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.54 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.54 |
| ▸ | ITGB5 | P18084 | 5/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | MC4R | P32245 | 5/20 | 0.47 |
| ▸ | MC5R | P33032 | 5/20 | 0.47 |
| ▸ | MC3R | P41968 | 5/20 | 0.47 |
| ▸ | MC1R | Q01726 | 5/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14885782 | 0.89 | ITGB3 (0.61) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL16177741 | 0.89 | ITGB3 (0.61) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL19581485 | 0.86 | ITGB3 (0.51) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL18970023 | 0.84 | ITGB3 (0.51) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL7744481 | 0.82 | ITGB3 (0.64) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL279121 | 0.82 | ITGB3 (0.64) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL23802907 | 0.82 | ITGB3 (0.46) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL16188466 | 0.79 | ITGB3 (0.48) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL14075705 | 0.79 | ITGB3 (0.53) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL22278847 | 0.78 | ITGB3 (0.52) | ITGB3ITGAVITGB1ITGA5ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9476883-B2 | Cellular recognition conjugates and methods of use for the histological analysis of cancer tissue using MALDI-MS imaging | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2016-10-25 | — | — | US | disclosed |
| US-20140315220-A1 | CELLULAR RECOGNITION CONJUGATES AND METHODS OF USE FOR THE HISTOLOGICAL ANALYSIS OF CANCER TISSUE USING MALDI-MS IMAGING | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2014-10-23 | — | — | US | disclosed |