Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 11/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16178561 | 0.76 | PI4KB (0.48) | PI4KB | |
| SCHEMBL16178451 | 0.72 | PI4KB (0.52) | PI4KB | |
| SCHEMBL603773 | 0.71 | HRH4 (0.54) | HRH4CHRNB2CHRNA4 | |
| SCHEMBL603774 | 0.71 | HRH4 (0.54) | HRH4CHRNB2CHRNA4 | |
| SCHEMBL14948613 | 0.71 | PI4KB (0.48) | PI4KB | |
| SCHEMBL3430563 | 0.71 | HRH4 (0.54) | HRH4CHRNB2CHRNA4 | |
| SCHEMBL16178464 | 0.71 | PI4KB (0.48) | PI4KB | |
| SCHEMBL17993458 | 0.70 | PI4KB (0.56) | PI4KB | |
| Hydrochloric Acid SCHEMBL16178577 | 0.70 | PI4KB (0.47) | PI4KB | |
| SCHEMBL16178571 | 0.69 | PI4KB (0.48) | HRH4PI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2776445-B1 | THERAPEUTICALLY ACTIVE THIAZOLO-PYRIMIDINE DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2016-08-10 | — | — | EP | disclosed |
| US-9096614-B2 | Therapeutically active thiazolo-pyrimidine derivatives | UCB PHARMA SA (BE) | 2015-08-04 | — | — | US | disclosed |
| US-20140315885-A1 | Therapeutically Active Thiazolo-Pyrimidine Derivatives | UCB PHARMA SA (BE) | 2014-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315885-A1 | Therapeutically Active Thiazolo-Pyrimidine Derivatives | TPMT, IFNG, IRF3 | HRH4 2766/4885CHRNB2 4410/4885CHRNA4 4475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.