SCHEMBL1617814

SCHEMBL1617814

CCn1c(C)c(C2(c3c(C)n(CC)c4ccccc34)OC(=O)c3ncccc32)c2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 2/20 0.44
GSK3B P49841 2/20 0.44
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 5/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
PTGER4 P35408 1/20 0.36
MAPK14 Q16539 1/20 0.36
NPY5R Q15761 1/20 0.36
LMNA P02545 2/20 0.34
HTT P42858 2/20 0.34
HPGD P15428 1/20 0.34
MAPK1 P28482 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C19 P33261 1/20 0.34
PKM P14618 1/20 0.34
TSHR P16473 1/20 0.34
RCE1 Q9Y256 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL211139 0.85 GSK3A (0.36) GSK3AGSK3BALDH1A1KDM4ESMN1; SMN2
SCHEMBL29735455 0.85 GSK3A (0.36) GSK3AGSK3BALDH1A1KDM4ESMN1; SMN2
SCHEMBL10937678 0.85 GSK3B (0.41) GSK3AGSK3BALDH1A1KDM4EMEN1
SCHEMBL25189936 0.84 GSK3A (0.35) GSK3AGSK3BALDH1A1KDM4ESMN1; SMN2
SCHEMBL11277671 0.84 KDM4E (0.36) GSK3AGSK3BALDH1A1KDM4ESMN1; SMN2
SCHEMBL8024670 0.83 GSK3A (0.36) GSK3AGSK3BALDH1A1KDM4ESMN1; SMN2
SCHEMBL30680380 0.83 ALDH1A1 (0.40) GSK3AGSK3BALDH1A1KDM4ESMN1; SMN2
SCHEMBL9358670 0.83 ALDH1A1 (0.40) GSK3AGSK3BALDH1A1KDM4ESMN1; SMN2
SCHEMBL11239203 0.82 GSK3A (0.42) GSK3AGSK3BALDH1A1KDM4ESMN1; SMN2
SCHEMBL211485 0.82 GSK3A (0.36) GSK3AGSK3BALDH1A1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7923488-B2 Leuco dyes with a N,N-dialkylamino, N,N-diarylamino, N-alkyl-N-arylamino, N-alkylamino, or N-arylamino group on one of the aromatic rings and a latent curing agent or catalyst activate-able by heat, pressure, or radiation TRILLION SCIENCE, INC. (US) 2011-04-12 US disclosed
US-20080090943-A1 Leuco dyes with a N,N-dialkylamino, N,N-diarylamino, N-alkyl-N-arylamino, N-alkylamino, or N-arylamino group on one of the aromatic rings and a latent curing agent or catalyst activate-able by heat, pressure, or radiation TRILLION, INC. 2008-04-17 US disclosed
US-7033581-B2 Method of treating hair with heat and a cap which provides a signal regarding treatment UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. (US) 2006-04-25 US disclosed
EP-1424918-B1 METHOD OF TREATING HAIR WITH HEAT AND A CAP WHICH PROVIDES A SIGNAL REGARDING TREATMENT UNILEVER PLC (GB) 2005-11-23 EP disclosed
US-20050074639-A1 Method of treating hair with heat and a cap which provides a signal regarding treatment UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2005-04-07 US disclosed
US-20030059459-A1 Method of treating hair with heat and a cap which provides a signal regarding treatment UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-03-27 US disclosed
EP-0390432-B1 Color-former JUJO PAPER CO LTD (JP) 1994-10-19 EP disclosed
EP-0395006-B1 Display composition, coloring pigment, and recording material SONY CORP (JP) 1994-08-31 EP disclosed
US-5178949-A Microcapsule with colorless dye, hydrophobic solvent, oil soluble nonionic surfactant JUJO PAPER CO., LTD. (JP) 1993-01-12 US disclosed
US-5179065-A Recording material with a display composition including a coloring pigment SONY CORPORATION (JP) 1993-01-12 US disclosed
US-5160371-A Leuco dye and quaternized clay SONY CORPORATION (JP) 1992-11-03 US disclosed
EP-0395006-A2 Display composition, coloring pigment, and recording material SONY CORPORATION (JP) 1990-10-31 EP disclosed
EP-0390432-A2 Color-former NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1990-10-03 EP disclosed
US-4957352-A Electrochromic display device SONY CORPORATION (JP) 1990-09-18 US disclosed
US-4828957-A Two-color heat-sensitive recording material with 2-hydroxy-3-naphthoanilide as both coupler and color developing agent KANZAKI PAPER MANUFACTURING COMPANY, LTD. (JP) 1989-05-09 US disclosed
EP-0301513-A2 Electrochromic display SONY CORPORATION (JP) 1989-02-01 EP disclosed
US-4580153-A COLOR FORMING BETWEEN COLORLESS CHROMOGENIC VINYL PHTHALIDE COMPOUND AND ELECTRON ACCEPTOR KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1986-04-01 US disclosed
US-4425161-A Thermochromic materials PILOT INK COMPANY, LTD., (JP) 1984-01-10 US disclosed