SCHEMBL8024670

SCHEMBL8024670

CCOc1cc(N(C)C)ccc1C1(c2c(C)n(CC)c3ccccc23)OC(=O)c2ncccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.36
GSK3B P49841 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.34
ALDH1A1 P00352 5/20 0.33
TP53 P04637 4/20 0.33
POLB P06746 1/20 0.33
THRB P10828 1/20 0.33
LYN P07948 1/20 0.33
SRC P12931 1/20 0.33
BTK Q06187 1/20 0.33
NPY5R Q15761 1/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 2/20 0.32
HPGD P15428 2/20 0.32
CYP3A4 P08684 2/20 0.32
BCL2 P10415 1/20 0.32
BAX Q07812 1/20 0.32
TSHR P16473 1/20 0.31
MAPT P10636 2/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL211485 0.93 GSK3A (0.36) GSK3AGSK3BSMN1; SMN2ALDH1A1TP53
SCHEMBL29735694 0.93 GSK3A (0.36) GSK3AGSK3BSMN1; SMN2ALDH1A1TP53
SCHEMBL8024221 0.91 SMN1; SMN2 (0.35) GSK3AGSK3BSMN1; SMN2ALDH1A1TP53
SCHEMBL25199444 0.91 ALDH1A1 (0.35) GSK3AGSK3BSMN1; SMN2ALDH1A1TP53
SCHEMBL3191798 0.89 CYP3A4 (0.35) GSK3AGSK3BSMN1; SMN2ALDH1A1TP53
SCHEMBL3234897 0.85 CNR2 (0.37) ALDH1A1POLBKDM4ELMNAHPGD
SCHEMBL21142029 0.84 PLA2G2A (0.32) GSK3AGSK3BSMN1; SMN2ALDH1A1LMNA
SCHEMBL3187839 0.84 CNR2 (0.40) ALDH1A1KDM4E
SCHEMBL3190107 0.84 CNR2 (0.39) ALDH1A1KDM4E
SCHEMBL3171252 0.84 CNR2 (0.39) ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0102132-A1 Reusable, heat-sensitive material APPLETON PAPERS INC. (US) 1984-03-07 EP claimed
US-4423116-A HEAT SENSITIVE CHROMOGENIC COMPOUND AND COLOR DEVELOPER IN BINDER APPLETON PAPERS INC. (US) 1983-12-27 US claimed
EP-0754564-B1 Heat sensitive recording material and recording method. MITSUBISHI PAPER MILLS LTD (JP) 2000-03-01 EP disclosed
US-5876898-A MULTICOLOR RECORDING OF HIGH CONTRAST MITSUBISHI PAPER MILLS LIMITED (JP) 1999-03-02 US disclosed
EP-0754564-A2 Heat sensitive recording material and recording method using the same MITSUBISHI PAPER MILLS, LTD. (JP) 1997-01-22 EP disclosed
US-4762818-A FLUORANE COLOR FORMER MITSUBISHI PAPER MILLS, LTD. (JP) 1988-08-09 US disclosed
US-4628337-A HIGH SPEED PHOTOPRINTING MITSUBISHI PAPER MILLS, LTD. (JP) 1986-12-09 US disclosed
EP-0102132-A1 Reusable, heat-sensitive material APPLETON PAPERS INC. (US) 1984-03-07 EP disclosed
US-4423116-A HEAT SENSITIVE CHROMOGENIC COMPOUND AND COLOR DEVELOPER IN BINDER APPLETON PAPERS INC. (US) 1983-12-27 US disclosed