Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Crotonic Acid SCHEMBL28083293 | 1.00 | TSHR (0.40) | TSHRTP53EGLN1EGLN3PTGS1 | |
| Crotonic Acid SCHEMBL16178258 | 1.00 | TSHR (0.40) | TSHRTP53EGLN1EGLN3PTGS1 | |
| Fumaric Acid SCHEMBL3815775 | 0.89 | TSHR (0.53) | TSHRTP53EGLN1EGLN3PTGS1 | |
| Crotonic Acid SCHEMBL27876744 | 0.85 | HTT (0.37) | TSHRTP53EGLN1EGLN3PTGS1 | |
| Crotonic Acid SCHEMBL28176555 | 0.83 | TSHR (0.50) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| Crotonic Acid SCHEMBL1759677 | 0.83 | TSHR (0.50) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| Crotonic Acid SCHEMBL9735696 | 0.83 | TSHR (0.50) | TSHRTP53EGLN1EGLN3ALDH1A1 | |
| SCHEMBL18814 | 0.83 | — | — | |
| SCHEMBL1396002 | 0.83 | FFAR3 (0.43) | TSHRPTGS1ALDH1A1ALOX15AKR1C3 | |
| Crotonic Acid SCHEMBL22034 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140315036-A1 | Ultraviolet-curable Resin Composition, Cured Product, and Optical Member | NIPPON KAYAKU KABUSHIKIKAISHA (JP) | 2014-10-23 | — | — | US | disclosed |