Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16177634 | 0.87 | SCN9A (0.75) | SLC22A12SCN9A | |
| SCHEMBL16178070 | 0.87 | SLC22A12 (1.00) | SLC22A12SCN9A | |
| SCHEMBL16531261 | 0.85 | SCN9A (1.00) | SCN9A | |
| SCHEMBL16530993 | 0.84 | SCN9A (1.00) | SLC22A12SCN9A | |
| SCHEMBL322817 | 0.84 | SCN9A (0.64) | SLC22A12SCN9A | |
| SCHEMBL16531867 | 0.83 | SCN9A (1.00) | SLC22A12SCN9A | |
| SCHEMBL16177820 | 0.83 | SCN9A (0.72) | SLC22A12SCN9A | |
| SCHEMBL16531429 | 0.83 | SCN9A (1.00) | SLC22A12SCN9A | |
| SCHEMBL16531537 | 0.82 | SCN9A (1.00) | SCN9A | |
| SCHEMBL16177848 | 0.82 | SCN9A (0.69) | SLC22A12SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014170793-A1 | SULFONAMIDES FOR THE TREATMENT OF GOUT | PFIZER LIMITED (GB) | 2014-10-23 | — | — | WO | disclosed |
| US-20140315933-A1 | CHEMICAL COMPOUNDS | PFIZER LIMITED (GB) | 2014-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315933-A1 | CHEMICAL COMPOUNDS | SULT2A1, SULT1A1, SULT1E1 | SLC22A12 1620/4885SCN9A 1724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.