Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 8/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | CBFB | Q13951 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16178363 | 0.89 | HTT (0.58) | KDM4EMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL1539980 | 0.80 | MAPT (0.97) | KDM4EMAPTHPGDALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL520889 | 0.79 | MAPT (1.00) | KDM4EMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL2026474 | 0.76 | HPGD (1.00) | KDM4EMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL23964352 | 0.76 | TDP1 (0.56) | KDM4EMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL13833222 | 0.75 | HPGD (0.97) | KDM4EMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL1540369 | 0.75 | MAPT (0.63) | KDM4EMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL2270689 | 0.74 | HRH3 (0.61) | MAPTALDH1A1ADRA2C | |
| SCHEMBL17592747 | 0.73 | OPRL1 (0.60) | MAPTHPGDALDH1A1HSD17B10OPRL1 | |
| SCHEMBL22640026 | 0.72 | DRD4 (0.57) | KDM4EMAPTHPGDALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096614-B2 | Therapeutically active thiazolo-pyrimidine derivatives | UCB PHARMA SA (BE) | 2015-08-04 | — | — | US | disclosed |
| US-20140315885-A1 | Therapeutically Active Thiazolo-Pyrimidine Derivatives | UCB PHARMA SA (BE) | 2014-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315885-A1 | Therapeutically Active Thiazolo-Pyrimidine Derivatives | TPMT, IFNG, IRF3 | KDM4E 1652/4885MAPT 2357/4885HPGD 615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.