SCHEMBL23964352

SCHEMBL23964352

Clc1ccc2nc(CN3CCNCC3)[nH]c2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.56
SOS1 Q07889 1/20 0.55
DRD4 P21917 3/20 0.53
MLLT1 Q03111 1/20 0.52
KDM4E B2RXH2 2/20 0.51
MAPT P10636 1/20 0.51
KMT2A Q03164 1/20 0.51
ATM Q13315 1/20 0.51
F10 P00742 2/20 0.50
HPGD P15428 4/20 0.49
ALDH1A1 P00352 3/20 0.49
HSD17B10 Q99714 2/20 0.49
HTT P42858 1/20 0.49
GRM2 Q14416 1/20 0.48
DRD2 P14416 1/20 0.48
RAB9A P51151 2/20 0.48
NPC1 O15118 1/20 0.48
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.48
NFKB1 P19838 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25180592 0.81 LMNA (0.56) TDP1DRD4MLLT1KDM4EMAPT
SCHEMBL8687149 0.81 DRD4 (0.74) DRD4HPGDALDH1A1HSD17B10GRM2
SCHEMBL23964235 0.80 RPS6KB1 (0.58) DRD4KDM4EMAPTATMHPGD
SCHEMBL22640026 0.80 DRD4 (0.57) DRD4KDM4EMAPTF10HPGD
SCHEMBL30041229 0.80 RPS6KB1 (0.58) DRD4KDM4EMAPTATMHPGD
SCHEMBL8690436 0.80 HTT (0.75) DRD4KDM4EHPGDALDH1A1HTT
SCHEMBL13833225 0.80 HTT (0.75) DRD4KDM4EHPGDALDH1A1HTT
SCHEMBL30225658 0.80 HTT (0.75) DRD4KDM4EHPGDALDH1A1HTT
Hydrochloric Acid SCHEMBL30040164 0.79 RPS6KB1 (0.57) DRD4KDM4EMAPTATMHPGD
SCHEMBL7476959 0.78 HTT (0.73) DRD4KDM4EHPGDALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 CN disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 CN disclosed
WO-2021216665-A9 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-02 WO disclosed
WO-2021216665-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 TDP1 1273/4885SOS1 1100/4885DRD4 4746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.