Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | USP25 | Q9UHP3 | 3/20 | 0.34 |
| ▸ | USP28 | Q96RU2 | 2/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16178782 | 0.82 | CYP3A4 (0.38) | NAMPTHRH4EPHX2ALDH1A1 | |
| SCHEMBL16178785 | 0.74 | EPHX2 (0.62) | RAB9AEPHX2MEN1ALDH1A1KMT2A | |
| SCHEMBL16178796 | 0.71 | KDM4E (0.35) | RAB9ANPC1HRH4KDM4EALDH1A1 | |
| SCHEMBL1907886 | 0.70 | PARP1 (0.43) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL5178524 | 0.69 | RAB9A (0.50) | RAB9ANAMPTSLC5A7NPC1HSP90AA1 | |
| SCHEMBL16178752 | 0.69 | MLNR (0.48) | EPHX2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL14941502 | 0.69 | EPHX2 (0.47) | EPHX2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL14335796 | 0.68 | CYP2D6 (0.49) | RAB9ANPC1EPHX2KDM4EMEN1 | |
| SCHEMBL16178776 | 0.68 | NTRK1 (0.41) | RAB9ANPC1HRH4USP25USP28 | |
| SCHEMBL13024405 | 0.67 | RAB9A (0.49) | RAB9ANAMPTNPC1HSP90AA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096614-B2 | Therapeutically active thiazolo-pyrimidine derivatives | UCB PHARMA SA (BE) | 2015-08-04 | — | — | US | disclosed |
| US-20140315885-A1 | Therapeutically Active Thiazolo-Pyrimidine Derivatives | UCB PHARMA SA (BE) | 2014-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315885-A1 | Therapeutically Active Thiazolo-Pyrimidine Derivatives | TPMT, IFNG, IRF3 | RAB9A 1399/4885NAMPT 289/4885SLC5A7 2073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.