Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11445122 | 0.81 | ALDH1A1 (0.45) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5143571 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL7711580 | 0.79 | ALDH1A1 (0.43) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL858260 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL10325478 | 0.75 | ALDH1A1 (0.41) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL141446 | 0.75 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AGAAHPGD | |
| SCHEMBL163958 | 0.74 | — | — | |
| SCHEMBL18982823 | 0.74 | — | — | |
| SCHEMBL30193793 | 0.74 | — | — | |
| SCHEMBL11240243 | 0.74 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106905316-B | Protein kinase inhibitors | 上海复尚慧创医药研究有限公司 | 2021-06-01 | — | — | CN | disclosed |
| EP-2986611-B1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) | 2019-02-06 | — | — | EP | disclosed |
| US-10022374-B2 | Certain protein kinase inhibitors | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2018-07-17 | — | — | US | disclosed |
| US-20170105994-A1 | CERTAIN PROTEIN KINASE INHIBITORS | Shanghai Fosun Pharmaceutical Industrial Development Co., Ltd. (CN) | 2017-04-20 | — | — | US | disclosed |
| US-9556171-B2 | Certain protein kinase inhibitors | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2017-01-31 | — | — | US | disclosed |
| US-20160083376-A1 | CERTAIN PROTEIN KINASE INHIBITORS | Shanghai Fosun Pharmaceutical Industrial Development Co., Ltd. (CN) | 2016-03-24 | — | — | US | disclosed |
| EP-2986611-A1 | CERTAIN PROTEIN KINASE INHIBITORS | Shanghai Fochon Pharmaceutical Co. Ltd (CN) | 2016-02-24 | — | — | EP | disclosed |
| WO-2014169843-A1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) | 2014-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170105994-A1 | CERTAIN PROTEIN KINASE INHIBITORS | PRKACA, PRKACB, PRKDC | ALDH1A1 4186/4885TSHR 2111/4885MEN1 4052/4885 |
| US-20160083376-A1 | CERTAIN PROTEIN KINASE INHIBITORS | PRKACA, PRKACB, PRKDC | ALDH1A1 4186/4885TSHR 2111/4885MEN1 4052/4885 |
| US-10022374-B2 | Certain protein kinase inhibitors | PRKACA, PRKACB, PRKDC | ALDH1A1 4186/4885TSHR 2111/4885MEN1 4052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.