Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 17/20 | 1.00 |
| ▸ | CCNT1 | O60563 | 15/20 | 1.00 |
| ▸ | CDK9 | P50750 | 15/20 | 1.00 |
| ▸ | CCNA2 | P20248 | 14/20 | 1.00 |
| ▸ | CDK1 | P06493 | 6/20 | 1.00 |
| ▸ | CDK4 | P11802 | 6/20 | 1.00 |
| ▸ | CCND1 | P24385 | 5/20 | 1.00 |
| ▸ | CDK7 | P50613 | 4/20 | 1.00 |
| ▸ | CCNK | O75909 | 3/20 | 1.00 |
| ▸ | CCNH | P51946 | 3/20 | 1.00 |
| ▸ | CCNE1 | P24864 | 3/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 3/20 | 1.00 |
| ▸ | CCND3 | P30281 | 2/20 | 1.00 |
| ▸ | CDK6 | Q00534 | 2/20 | 1.00 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 1.00 |
| ▸ | CCNO | P22674 | 1/20 | 1.00 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.68 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.68 |
| ▸ | GSK3A | P49840 | 3/20 | 0.68 |
| ▸ | GSK3B | P49841 | 3/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21622452 | 1.00 | CDK2 (1.00) | CDK2CCNT1CDK9CCNA2CDK1 | |
| SCHEMBL16189638 | 1.00 | CDK2 (1.00) | CDK2CCNT1CDK9CCNA2CDK1 | |
| SCHEMBL31028540 | 1.00 | CDK2 (1.00) | CDK2CCNT1CDK9CCNA2CDK1 | |
| SCHEMBL21618367 | 1.00 | CDK2 (1.00) | CDK2CCNT1CDK9CCNA2CDK1 | |
| SCHEMBL21622451 | 1.00 | CDK2 (1.00) | CDK2CCNT1CDK9CCNA2CDK1 | |
| Hydrochloric Acid SCHEMBL16180173 | 0.99 | CDK2 (0.98) | CDK2CCNT1CDK9CCNA2CDK1 | |
| Hydrochloric Acid SCHEMBL16180132 | 0.99 | CDK2 (0.98) | CDK2CCNT1CDK9CCNA2CDK1 | |
| SCHEMBL19595599 | 0.96 | CDK2 (0.92) | CDK2CCNT1CDK9CCNA2CDK1 | |
| SCHEMBL16189635 | 0.89 | CDK9 (1.00) | CDK2CCNT1CDK9CCNA2CDK1 | |
| SCHEMBL16180018 | 0.89 | CDK9 (1.00) | CDK2CCNT1CDK9CCNA2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820451-B1 | SOLID DISPERSION COMPRISING AN ANTICANCER COMPOUND WITH IMPROVED SOLUBILITY AND EFFICACY | COUNCIL SCIENT IND RES (IN) | 2024-07-24 | — | — | EP | claimed |
| US-12036214-B2 | Solid dispersion comprising an anticancer compound for improved solubility and efficacy | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH [IN/IN] (IN) | 2024-07-16 | — | — | US | claimed |
| US-20210308116-A1 | SOLID DISPERSION COMPRISING AN ANTICANCER COMPOUND FOR IMPROVED SOLUBILITY AND EFFICACY | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH [IN/IN] (IN) | 2021-10-07 | — | — | US | claimed |
| EP-3820451-A1 | SOLID DISPERSION COMPRISING AN ANTICANCER COMPOUND WITH IMPROVED SOLUBILITY AND EFFICACY | Council Of Scientific & Industrial Research (IN) | 2021-05-19 | — | — | EP | claimed |
| WO-2020012498-A1 | SOLID DISPERSION COMPRISING AN ANTICANCER COMPOUND WITH IMPROVED SOLUBILITY AND EFFICACY | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-01-16 | — | — | WO | claimed |
| EP-3820451-B1 | SOLID DISPERSION COMPRISING AN ANTICANCER COMPOUND WITH IMPROVED SOLUBILITY AND EFFICACY | COUNCIL SCIENT IND RES (IN) | 2024-07-24 | — | — | EP | disclosed |
| US-12036214-B2 | Solid dispersion comprising an anticancer compound for improved solubility and efficacy | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH [IN/IN] (IN) | 2024-07-16 | — | — | US | disclosed |
| US-20210308116-A1 | SOLID DISPERSION COMPRISING AN ANTICANCER COMPOUND FOR IMPROVED SOLUBILITY AND EFFICACY | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH [IN/IN] (IN) | 2021-10-07 | — | — | US | disclosed |
| EP-3820451-A1 | SOLID DISPERSION COMPRISING AN ANTICANCER COMPOUND WITH IMPROVED SOLUBILITY AND EFFICACY | Council Of Scientific & Industrial Research (IN) | 2021-05-19 | — | — | EP | disclosed |
| WO-2020012498-A1 | SOLID DISPERSION COMPRISING AN ANTICANCER COMPOUND WITH IMPROVED SOLUBILITY AND EFFICACY | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-01-16 | — | — | WO | disclosed |
| US-9932327-B2 | Rohitukine analogs as cyclin-dependent kinase inhibitors and a process for the preparation thereof | THE COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-04-03 | — | — | US | disclosed |
| EP-2986605-B1 | ROHITUKINE ANALOGS AS CYCLIN-DEPENDENT KINASE INHIBITORS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2017-11-15 | — | — | EP | disclosed |
| US-20160052915-A1 | ROHITUKINE ANALOGS AS CYCLIN-DEPENDENT KINASE INHIBITORS AND A PROCESS FOR THE PREPARATION THEREOF | THE COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-02-25 | — | — | US | disclosed |
| EP-2986605-A1 | ROHITUKINE ANALOGS AS CYCLIN-DEPENDENT KINASE INHIBITORS AND A PROCESS FOR THE PREPARATION THEREOF | Council of Scientific and Industrial Research (IN) | 2016-02-24 | — | — | EP | disclosed |
| WO-2014170914-A1 | ROHITUKINE ANALOGS AS CYCLIN-DEPENDENT KINASE INHIBITORS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210308116-A1 | SOLID DISPERSION COMPRISING AN ANTICANCER COMPOUND FOR IMPROVED SOLUBILITY AND EFFICACY | ABCG2, CCND1, TP53 | CDK2 65/4885CCNT1 20/4885CDK9 54/4885 |
| US-20160052915-A1 | ROHITUKINE ANALOGS AS CYCLIN-DEPENDENT KINASE INHIBITORS AND A PROCESS FOR THE PREPARATION THEREOF | CCNK, CDK1, CDK2 | CDK2 3/4885CCNT1 47/4885CDK9 21/4885 |
| US-12036214-B2 | Solid dispersion comprising an anticancer compound for improved solubility and efficacy | ABCG2, CCND1, TP53 | CDK2 65/4885CCNT1 20/4885CDK9 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.