Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 17/20 | 0.92 |
| ▸ | CCNT1 | O60563 | 15/20 | 0.92 |
| ▸ | CDK9 | P50750 | 15/20 | 0.92 |
| ▸ | CCNA2 | P20248 | 14/20 | 0.92 |
| ▸ | CDK1 | P06493 | 6/20 | 0.92 |
| ▸ | CDK4 | P11802 | 6/20 | 0.92 |
| ▸ | CCND1 | P24385 | 5/20 | 0.92 |
| ▸ | CDK7 | P50613 | 4/20 | 0.92 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.92 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.92 |
| ▸ | CCNK | O75909 | 3/20 | 0.92 |
| ▸ | CCNH | P51946 | 3/20 | 0.92 |
| ▸ | CCND3 | P30281 | 2/20 | 0.92 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.92 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.92 |
| ▸ | CCNO | P22674 | 1/20 | 0.92 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.65 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.65 |
| ▸ | GSK3A | P49840 | 3/20 | 0.65 |
| ▸ | GSK3B | P49841 | 3/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21618367 | 0.96 | CDK2 (1.00) | CDK2CCNT1CDK9CCNA2CDK1 | |
| SCHEMBL31028540 | 0.96 | CDK2 (1.00) | CDK2CCNT1CDK9CCNA2CDK1 | |
| SCHEMBL21622452 | 0.96 | CDK2 (1.00) | CDK2CCNT1CDK9CCNA2CDK1 | |
| SCHEMBL16189638 | 0.96 | CDK2 (1.00) | CDK2CCNT1CDK9CCNA2CDK1 | |
| SCHEMBL21622451 | 0.96 | CDK2 (1.00) | CDK2CCNT1CDK9CCNA2CDK1 | |
| SCHEMBL16179628 | 0.96 | CDK2 (1.00) | CDK2CCNT1CDK9CCNA2CDK1 | |
| Hydrochloric Acid SCHEMBL16180173 | 0.95 | CDK2 (0.98) | CDK2CCNT1CDK9CCNA2CDK1 | |
| Hydrochloric Acid SCHEMBL16180132 | 0.95 | CDK2 (0.98) | CDK2CCNT1CDK9CCNA2CDK1 | |
| SCHEMBL16180018 | 0.86 | CDK9 (1.00) | CDK2CCNT1CDK9CCNA2CDK1 | |
| SCHEMBL16189635 | 0.86 | CDK9 (1.00) | CDK2CCNT1CDK9CCNA2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2986605-B1 | ROHITUKINE ANALOGS AS CYCLIN-DEPENDENT KINASE INHIBITORS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2017-11-15 | — | — | EP | disclosed |