Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 7/20 | 0.44 |
| ▸ | FEN1 | P39748 | 7/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1744740 | 0.86 | ALOX5AP (0.55) | ALOX5APFEN1CA1CA2CA12 | |
| Orthocresol SCHEMBL16180579 | 0.85 | ALOX5AP (0.45) | ALOX5APFEN1CA1CA2KDM1A | |
| SCHEMBL16180470 | 0.85 | ALOX5AP (0.47) | ALOX5APFEN1KDM1ACA9PTGS1 | |
| 2-Chlorophenol SCHEMBL16180513 | 0.83 | ALOX5AP (0.45) | ALOX5APFEN1CA1CA2KDM1A | |
| SCHEMBL16180522 | 0.82 | ALOX5AP (0.43) | ALOX5APFEN1KDM1ACA9MEN1 | |
| SCHEMBL16180634 | 0.82 | ALOX5AP (0.47) | ALOX5APFEN1KDM1A | |
| SCHEMBL16180585 | 0.80 | ALOX5AP (0.43) | ALOX5APFEN1CA2CA12CA9 | |
| SCHEMBL24497548 | 0.76 | METAP2 (0.51) | ALOX5APFEN1TSHRKDM1AFYN | |
| Guaiacol SCHEMBL16180573 | 0.74 | CA1 (0.43) | CA1CA2TP53TSHRCA12 | |
| SCHEMBL27876969 | 0.73 | KDM1A (0.51) | ALOX5APFEN1CA1TP53KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014170792-A1 | SULFONAMIDE DERIVATIVES AS URAT-1 INHIBITORS | PFIZER LIMITED (GB) | 2014-10-23 | — | — | WO | disclosed |