Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10195527 | 0.91 | MEN1 (0.33) | MEN1HTTKMT2AATMSCN9A | |
| SCHEMBL10195400 | 0.91 | CYP1A2 (0.37) | ALDH1A1HPGDHTTSCN9ASCN10A | |
| SCHEMBL10195520 | 0.91 | HTT (0.38) | MEN1NPC1ALDH1A1HPGDHTT | |
| SCHEMBL10195518 | 0.88 | SCN9A (0.32) | ALDH1A1HPGDSCN9ASCN10A | |
| SCHEMBL16180988 | 0.87 | ALDH1A1 (0.37) | MEN1NPC1ALDH1A1HPGDHTT | |
| SCHEMBL16351649 | 0.83 | LPAR1 (0.35) | ALDH1A1HPGD | |
| SCHEMBL10195324 | 0.81 | SCN9A (0.35) | SCN9ASCN10A | |
| SCHEMBL16351650 | 0.80 | MAPK14 (0.32) | — | |
| SCHEMBL16351657 | 0.80 | HTR2A (0.33) | — | |
| SCHEMBL10195460 | 0.79 | CYP11B2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865623-B2 | Herbicidally active cyclic diones and derivatives thereof, processes for their preparation, compositions, and method of controlling weeds | SYNGENTA LIMITED (GB) | 2014-10-21 | — | — | US | disclosed |