Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902326 | 0.83 | HTT (0.48) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL6686553 | 0.74 | MEN1 (0.46) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL6687986 | 0.71 | ALOX12 (0.47) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL7625869 | 0.68 | HTT (0.63) | KMT2AMEN1HTTSMN1; SMN2CYP3A4 | |
| SCHEMBL10521791 | 0.67 | ESR1 (0.58) | KMT2AMEN1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8846854 | 0.67 | ESR1 (0.58) | KMT2AMEN1LMNAHTTSMN1; SMN2 | |
| SCHEMBL6687981 | 0.66 | MEN1 (0.55) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL6686042 | 0.66 | ALOX12 (0.50) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL28945161 | 0.66 | ALDH1A1 (0.54) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL9973111 | 0.65 | MEN1 (0.74) | KMT2AMEN1MAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865684-B2 | Morpholin-4-ium 4 methoxyphenyl (morpholino) phosphinodithioate (GYY4137) as a novel vasodilator agent | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2014-10-21 | — | — | US | disclosed |