Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 16/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 10/20 | 0.54 |
| ▸ | NPY1R | P25929 | 9/20 | 0.54 |
| ▸ | NPY2R | P49146 | 7/20 | 0.54 |
| ▸ | FURIN | P09958 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16181283 | 0.99 | NPY4R (0.53) | NPY4RNPY5RNPY1RNPY2RFURIN | |
| SCHEMBL16181294 | 0.96 | NPY4R (0.52) | NPY4RNPY5RNPY1RNPY2RFURIN | |
| SCHEMBL16181295 | 0.95 | NPY4R (0.51) | NPY4RNPY5RNPY1RNPY2RFURIN | |
| SCHEMBL16181273 | 0.94 | NPY4R (0.55) | NPY4RNPY5RNPY1RNPY2RFURIN | |
| SCHEMBL16181279 | 0.90 | FURIN (0.48) | NPY4RNPY5RNPY1RNPY2RFURIN | |
| SCHEMBL16181289 | 0.90 | NPY4R (0.53) | NPY4RNPY5RNPY1RNPY2RFURIN | |
| SCHEMBL16181250 | 0.90 | NPY4R (0.53) | NPY4RNPY5RNPY1RNPY2RFURIN | |
| SCHEMBL16502366 | 0.90 | NPY4R (0.53) | NPY4RNPY5RNPY1RNPY2RFURIN | |
| SCHEMBL16181243 | 0.90 | NPY4R (0.53) | NPY4RNPY5RNPY1RNPY2RFURIN | |
| SCHEMBL16181246 | 0.90 | NPY4R (0.53) | NPY4RNPY5RNPY1RNPY2RFURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865865-B2 | N-terminally modified tetrapeptide derivatives having a C-terminal arginine mimetic | PHILIPPS-UNIVERSITAT MARBURG (DE) | 2014-10-21 | — | — | US | disclosed |