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SCHEMBL16181283

SCHEMBL16181283

CC(=N)c1ccc(CNC(=O)[C@H](CCCNC(=N)N)NC(=O)C(NC(=O)[C@H](CCCNC(=N)N)NC(=O)CCCCNC(=N)N)C(C)C)cc1

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 17/20 0.53
▸ NPY5R Q15761 10/20 0.53
▸ NPY1R P25929 9/20 0.53
▸ NPY2R P49146 7/20 0.53
▸ FURIN P09958 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16181270 0.99 NPY4R (0.54) NPY4RNPY5RNPY1RNPY2RFURIN
SCHEMBL16181295 0.96 NPY4R (0.51) NPY4RNPY5RNPY1RNPY2RFURIN
SCHEMBL16181294 0.95 NPY4R (0.52) NPY4RNPY5RNPY1RNPY2RFURIN
SCHEMBL16181273 0.93 NPY4R (0.55) NPY4RNPY5RNPY1RNPY2RFURIN
SCHEMBL16181279 0.91 FURIN (0.48) NPY4RNPY5RNPY1RNPY2RFURIN
SCHEMBL16181276 0.90 NPY4R (0.51) NPY4RNPY5RNPY1RNPY2RFURIN
SCHEMBL16181291 0.90 NPY4R (0.51) NPY4RNPY5RNPY1RNPY2RFURIN
SCHEMBL16181271 0.89 NPY4R (0.45) NPY4RNPY5RNPY1RNPY2RFURIN
SCHEMBL16181250 0.89 NPY4R (0.53) NPY4RNPY5RNPY1RNPY2RFURIN
SCHEMBL16181245 0.89 NPY4R (0.53) NPY4RNPY5RNPY1RNPY2RFURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8865865-B2 N-terminally modified tetrapeptide derivatives having a C-terminal arginine mimetic PHILIPPS-UNIVERSITAT MARBURG (DE) 2014-10-21 — — US disclosed
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