Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 5/20 | 0.48 |
| ▸ | NPY4R | P50391 | 13/20 | 0.45 |
| ▸ | NPY1R | P25929 | 9/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.45 |
| ▸ | NPY2R | P49146 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16181274 | 0.96 | NPY1R (0.51) | FURINNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL16181272 | 0.96 | FURIN (0.51) | FURINNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL16181278 | 0.94 | FURIN (0.54) | FURINNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL16181269 | 0.92 | FURIN (0.43) | FURINNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL16181283 | 0.91 | NPY4R (0.53) | FURINNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL16181270 | 0.90 | NPY4R (0.54) | FURINNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL16181237 | 0.90 | FURIN (0.52) | FURINNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL7920067 | 0.90 | FURIN (0.52) | FURINNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL16181609 | 0.90 | FURIN (0.52) | FURINNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL16181267 | 0.90 | FURIN (0.52) | FURINNPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865865-B2 | N-terminally modified tetrapeptide derivatives having a C-terminal arginine mimetic | PHILIPPS-UNIVERSITAT MARBURG (DE) | 2014-10-21 | — | — | US | disclosed |