Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14680248 | 0.82 | POLB (0.55) | POLBMAPTHSP90AA1GPR55MEN1 | |
| SCHEMBL1703604 | 0.79 | POLB (0.61) | POLBMAPTHSP90AA1GPR55MEN1 | |
| SCHEMBL11123690 | 0.79 | MAPT (0.57) | POLBMAPTHSP90AA1GPR55MEN1 | |
| SCHEMBL3641542 | 0.79 | MAPT (0.56) | POLBMAPTHSP90AA1GPR55MEN1 | |
| SCHEMBL17028022 | 0.77 | HDAC2 (0.49) | POLBMAPTHSP90AA1GPR55MEN1 | |
| SCHEMBL29077383 | 0.76 | POLB (0.57) | POLBMAPTHSP90AA1GPR55MEN1 | |
| SCHEMBL10435602 | 0.76 | MAPT (0.61) | POLBMAPTHSP90AA1GPR55MEN1 | |
| SCHEMBL9676988 | 0.76 | POLB (0.57) | POLBMAPTHSP90AA1GPR55MEN1 | |
| SCHEMBL7939406 | 0.76 | MEN1 (0.61) | POLBMAPTHSP90AA1GPR55MEN1 | |
| SCHEMBL9819108 | 0.75 | POLB (0.47) | POLBMAPTHSP90AA1GPR55MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865820-B2 | Fluorine-containing curable composition and rubber article | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-10-21 | — | — | US | disclosed |