Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 4/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14680248 | 0.78 | POLB (0.55) | HDAC2HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL16181541 | 0.77 | POLB (0.53) | HDAC2HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL3641542 | 0.75 | MAPT (0.56) | POLBMAPTHSP90AA1GPR55ALDH1A1 | |
| SCHEMBL11123690 | 0.75 | MAPT (0.57) | HDAC2HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL13337463 | 0.73 | POLB (0.53) | HDAC2HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL1703604 | 0.71 | POLB (0.61) | HDAC1POLBMAPTHSP90AA1GPR55 | |
| SCHEMBL7829245 | 0.71 | MAPT (0.49) | POLBMAPTHSP90AA1GPR55ALDH1A1 | |
| SCHEMBL9819108 | 0.71 | POLB (0.47) | POLBMAPTHSP90AA1GPR55ALDH1A1 | |
| SCHEMBL11879432 | 0.70 | MEN1 (0.54) | HDAC2HDAC1HDAC8HDAC6HDAC3 | |
| SCHEMBL21626142 | 0.69 | MAPT (0.54) | POLBMAPTHSP90AA1GPR55ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015126930-A2 | BOOSTER DRUG THERAPY FOR MYCOBACTERIUM INFECTIONS | STC.UNM (US) | 2015-08-27 | — | — | WO | claimed |