⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18977366 | 0.85 | — | — | |
| SCHEMBL8442364 | 0.71 | ALDH1A1 (0.30) | — | |
| SCHEMBL9045234 | 0.71 | — | — | |
| SCHEMBL6587598 | 0.68 | — | — | |
| SCHEMBL4871844 | 0.68 | CCR5 (0.33) | — | |
| SCHEMBL11298692 | 0.67 | — | — | |
| SCHEMBL6058575 | 0.66 | ALDH1A1 (0.30) | — | |
| SCHEMBL15479683 | 0.66 | — | — | |
| SCHEMBL24289006 | 0.65 | — | — | |
| SCHEMBL18026830 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262805-B1 | POLYSUBSTITUTED DERIVATIVES OF 2-HETEROARYL-6-PHENYL-IMIDAZO[L,2-A] PYRIDINES, AND PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2014-10-22 | — | — | EP | disclosed |