Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.65 |
| ▸ | BLM | P54132 | 2/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.65 |
| ▸ | MPO | P05164 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | KDM5A | P29375 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28830270 | 0.83 | CYP1A2 (0.70) | GFERBLMPMP22HIF1AMPO | |
| SCHEMBL1161862 | 0.82 | GFER (0.64) | GFERBLMPMP22HIF1AMPO | |
| Hydrochloric Acid SCHEMBL32665514 | 0.82 | BLM (0.71) | GFERBLMPMP22HIF1AMPO | |
| SCHEMBL1696266 | 0.81 | NPC1 (0.54) | NPC1RAB9AHDAC1MEN1KMT2A | |
| SCHEMBL17299368 | 0.81 | CA12 (0.50) | BLMPMP22HIF1AMAPTCYP1A2 | |
| SCHEMBL13009911 | 0.81 | HDAC6 (0.68) | BLMPMP22HIF1AMAPTCYP1A2 | |
| SCHEMBL47366 | 0.81 | CYP1A2 (0.72) | GFERBLMPMP22MAPTCYP1A2 | |
| SCHEMBL17623623 | 0.80 | HDAC3 (0.59) | GFERBLMPMP22HIF1AMPO | |
| SCHEMBL948542 | 0.80 | GAA (0.68) | MAPTNPC1GAARAB9ASMN1; SMN2 | |
| SCHEMBL80530 | 0.79 | MPO (1.00) | GFERBLMPMP22HIF1AMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582696-B1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING PESTS | NOVARTIS AG (CH) | 2014-10-22 | — | — | EP | disclosed |