Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.72 |
| ▸ | MAOB | P27338 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3506361 | 0.84 | MAOB (1.00) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL9584535 | 0.83 | CYP1A2 (0.78) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| Hydrochloric Acid SCHEMBL2799201 | 0.82 | KMT2A (1.00) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| Hydrochloric Acid SCHEMBL663099 | 0.82 | KMT2A (1.00) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL6859638 | 0.81 | CYP1A2 (0.80) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL3363697 | 0.81 | CYP1A2 (0.63) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL16181982 | 0.81 | GFER (0.65) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL165164 | 0.80 | MAPT (1.00) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL11004530 | 0.80 | MEN1 (0.58) | CYP1A2TSHRNFKB1MAOBMEN1 | |
| SCHEMBL5038583 | 0.80 | CYP1A2 (0.62) | CYP1A2TSHRNFKB1MAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582696-B1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING PESTS | NOVARTIS AG (CH) | 2014-10-22 | — | — | EP | disclosed |
| WO-2011157748-A1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING PESTS | NOVARTIS AG (CH) | 2011-12-22 | — | — | WO | disclosed |