SCHEMBL1618482

SCHEMBL1618482

C=CN1CCC(CC)CC1=O

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
BRD4 O60885 1/20 0.31
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7236820 0.90 MEN1 (0.30) MEN1RAB9AKMT2A
SCHEMBL1618413 0.86 OPRM1 (0.33) BRD4
SCHEMBL7236142 0.84 MEN1 (0.30) MEN1RAB9AKMT2A
SCHEMBL5163308 0.83 CYP1A2 (0.41) MEN1KMT2A
SCHEMBL631765 0.81 BRD4 (0.36) BRD4
SCHEMBL7238106 0.77 OPRM1 (0.34)
SCHEMBL35410 0.76 ALDH1A1 (0.34)
SCHEMBL868862 0.74 CYP1A2 (0.41)
SCHEMBL23132786 0.73 BRD4 (0.47) BRD4NOS3NOS1NOS2
SCHEMBL12424595 0.73 BRD4 (0.47) BRD4NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101657511-B Composition for coating over a photoresist pattern comprising a lactam AZ ELECTRONIC MATERIALS USA 2015-02-04 CN disclosed
EP-2158277-B1 AQUEOUS COMPOSITION COMPRISING LACTAM FOR COATING OVER A PHOTORESIST PATTERN AZ ELECTRONIC MATERIALS USA (US) 2014-03-05 EP disclosed
US-8288496-B2 Contact lens and its manufacturing method NIPPON CONTACT LENS INC. (JP) 2012-10-16 US disclosed
US-20120219919-A1 Composition for Coating over a Photoresist Pattern Comprising a Lactam THIYAGARAJAN MUTHIAH (US) 2012-08-30 US disclosed
CN-102272675-A A photoresist image-forming process using double patterning 2011-12-07 CN disclosed
EP-2389612-A1 A PHOTORESIST IMAGE-FORMING PROCESS USING DOUBLE PATTERNING AZ Electronic Materials USA Corp. (US) 2011-11-30 EP disclosed
US-20110237701-A1 CONTACT LENS AND ITS MANUFACTURING METHOD NIPPON CONTACT LENS INC. (JP) 2011-09-29 US disclosed
EP-2369370-A2 Contact lens and its manufacturing method Nippon Contact Lens Inc. (JP) 2011-09-28 EP disclosed
US-7923200-B2 Polyvinylcaprolactam based; for production of microelectronics AZ ELECTRONIC MATERIALS USA CORP. (US) 2011-04-12 US disclosed
WO-2010084372-A1 A PHOTORESIST IMAGE-FORMING PROCESS USING DOUBLE PATTERNING AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-07-29 WO disclosed
US-20100183851-A1 Photoresist Image-forming Process Using Double Patterning CAO YI 2010-07-22 US disclosed
EP-2158277-A2 A COMPOSITION FOR COATING OVER A PHOTORESIST PATTERN COMPRISING A LACTEM AZ Electronic Materials USA Corp. (US) 2010-03-03 EP disclosed
CN-101657511-A The composition that contains lactan that is used on the photo-resist pattern, applying AZ ELECTRONIC MATERIALS USA US 2010-02-24 CN disclosed
WO-2008122884-A2 A COMPOSITION FOR COATING OVER A PHOTORESIST PATTERN COMPRISING A LACTEM AZ ELECTRONIC MATERIALS USA CORP. (DE) 2008-10-16 WO disclosed
US-20080248427-A1 Composition for Coating over a Photoresist Pattern Comprising a Lactam MERCK PATENT GMBH (DE) 2008-10-09 US disclosed
US-6583281-B2 Using phenothiazine BASF AKTIENGESELLSCHAFT (DE) 2003-06-24 US disclosed
US-20020002280-A1 Stabilized N-alkenyllactam BASF AKTIENGESELLSCHAFT (DE) 2002-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020002280-A1 Stabilized N-alkenyllactam ALK, NPM1, MYC MEN1 774/4885RAB9A 2779/4885KMT2A 170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.