Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 8/20 | 0.39 |
| ▸ | MMP9 | P14780 | 4/20 | 0.35 |
| ▸ | MMP13 | P45452 | 4/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16177637 | 0.91 | SLC22A12 (0.40) | SLC22A12MMP9MMP13MMP2MMP8 | |
| SCHEMBL16185267 | 0.87 | SLC22A12 (0.41) | SLC22A12MMP9MMP13MMP2MMP8 | |
| SCHEMBL16185280 | 0.84 | SLC22A12 (0.39) | SLC22A12PTGDR2AVPR2OXTRAVPR1A | |
| SCHEMBL16185262 | 0.84 | SLC22A12 (0.39) | SLC22A12PTGDR2AVPR2OXTRAVPR1A | |
| SCHEMBL16185269 | 0.83 | SLC22A12 (0.49) | SLC22A12 | |
| SCHEMBL16185279 | 0.83 | SLC22A12 (0.41) | SLC22A12AVPR2OXTRAVPR1AALDH1A1 | |
| SCHEMBL16178082 | 0.81 | SLC22A12 (0.40) | SLC22A12PTGDR2HSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL16185266 | 0.81 | SLC22A12 (0.46) | SLC22A12 | |
| SCHEMBL18352242 | 0.81 | SLC22A12 (0.39) | SLC22A12 | |
| SCHEMBL9923641 | 0.79 | SCN9A (0.42) | SLC22A12AVPR2OXTRAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150259327-A1 | Chemical Compounds | PFIZER LIMITED (GB) | 2015-09-17 | — | — | US | disclosed |
| US-9067922-B2 | Chemical compounds | PFIZER LIMITED (GB) | 2015-06-30 | — | — | US | disclosed |
| US-20140315878-A1 | CHEMICAL COMPOUNDS | PFIZER LIMITED (GB) | 2014-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150259327-A1 | Chemical Compounds | SULT2A1, SULT1A1, SULT1E1 | SLC22A12 1128/4885MMP9 4398/4885MMP13 4588/4885 |
| US-20140315878-A1 | CHEMICAL COMPOUNDS | SULT2A1, SULT1A1, SULT1E1 | SLC22A12 1128/4885MMP9 4398/4885MMP13 4588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.