SCHEMBL1618639

SCHEMBL1618639

COc1ccc(Nc2ccc(N)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR4A1 P22736 1/20 1.00
▸ MAPT P10636 8/20 0.77
▸ GAA P10253 6/20 0.77
▸ RAB9A P51151 5/20 0.77
▸ TDP1 Q9NUW8 4/20 0.77
▸ L3MBTL1 Q9Y468 4/20 0.77
▸ MAPK1 P28482 3/20 0.77
▸ KDM4E B2RXH2 3/20 0.77
▸ THRB P10828 2/20 0.77
▸ RECQL P46063 2/20 0.77
▸ NPC1 O15118 2/20 0.77
▸ NPSR1 Q6W5P4 1/20 0.77
▸ ALDH1A1 P00352 7/20 0.70
▸ CYP3A4 P08684 2/20 0.70
▸ APP P05067 2/20 0.57
▸ HTT P42858 3/20 0.56
▸ MEN1 O00255 3/20 0.56
▸ KMT2A Q03164 3/20 0.56
▸ MMP14 P50281 1/20 0.56
▸ CYP1A2 P05177 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6389088 0.98 NR4A1 (0.96) NR4A1MAPTGAARAB9ATDP1
SCHEMBL27956260 0.94 NR4A1 (0.88) NR4A1MAPTGAARAB9ATDP1
SCHEMBL11764736 0.92 NR4A1 (0.85) NR4A1MAPTGAARAB9ATDP1
Sulfuric Acid SCHEMBL11419340 0.89 NR4A1 (0.79) NR4A1MAPTGAARAB9ATDP1
SCHEMBL30511913 0.89 NR4A1 (0.79) NR4A1MAPTGAARAB9ATDP1
Sulfuric Acid SCHEMBL29722524 0.89 NR4A1 (0.79) NR4A1MAPTGAARAB9ATDP1
SCHEMBL39057 0.88 MAPT (1.00) NR4A1MAPTGAARAB9ATDP1
SCHEMBL1459772 0.88 MAPT (1.00) NR4A1MAPTGAARAB9ATDP1
SCHEMBL22931133 0.86 NR4A1 (0.76) NR4A1MAPTGAARAB9ATDP1
SCHEMBL5097 0.85 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 559 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4511649-B1 METHOD AND KIT FOR THE DETECTION OF CHROMIUM-6 IN A SAMPLE SEEF B V (NL) 2026-03-11 — — EP claimed
US-20250243317-A1 AMINO DIPHENYLAMINE-STARTED POLYETHER POLYOLS, METHODS FOR THEIR PRODUCTION, AND FLEXIBLE POLYURETHANE FOAMS PRODUCED USING SUCH POLYOLS COVESTRO LLC (US) 2025-07-31 — — US claimed
CN-118903081-A Application of metabolite in preparation of medicine for preventing or treating bronchopulmonary dysplasia 无锡市儿童医院 2024-11-08 — — CN claimed
US-12116449-B2 Polyethers and their use in the production of flexible polyurethane foams COVESTRO LLC (US) 2024-10-15 — — US claimed
EP-3198281-B1 ELLAGIC ACID FORMULATIONS FOR USE IN COAGULATION ASSAYS ABBOTT POINT OF CARE INC (US) 2023-01-25 — — EP claimed
US-20220267506-A1 POLYETHERS AND THEIR USE IN THE PRODUCTION OF FLEXIBLE POLYURETHANE FOAMS COVESTRO LLC (US) 2022-08-25 — — US claimed
US-20220267507-A1 AMINO DIPHENYLAMINE-STARTED POLYETHER POLYOLS, METHODS FOR THEIR PRODUCTION, AND FLEXIBLE POLYURETHANE FOAMS PRODUCED USING SUCH POLYOLS COVESTRO LLC 2022-08-25 — — US claimed
EP-3997147-A1 POLYETHERS AND THEIR USE IN THE PRODUCTION OF FLEXIBLE POLYURETHANE FOAMS Covestro LLC (US) 2022-05-18 — — EP claimed
EP-3997148-A1 AMINO DIPHENYLAMINE-STARTED POLYETHER POLYOLS, METHODS FOR THEIR PRODUCTION, AND FLEXIBLE POLYURETHANE FOAMS PRODUCED USING SUCH POLYOLS Covestro LLC (US) 2022-05-18 — — EP claimed
EP-3997150-A1 POLYMER POLYOL COMPOSITIONS AND THEIR USE IN THE PRODUCTION OF FLEXIBLE POLYURETHANE FOAMS Covestro LLC (US) 2022-05-18 — — EP claimed
EP-0606858-B1 Liquid crystal compositions and liquid crystal display devices CHISSO CORP (JP) 2000-04-26 — — EP claimed
US-5723065-A CONDENSED HETEROCYCLE AND AROMATIC AMINE, ALIPHATIC AMINE AND FLUOROCYANOPHENOL CHISSO CORPORATION (JP) 1998-03-03 — — US claimed
EP-0567207-B1 Method of reducing impurities in aqueous monomer solutions ROHM & HAAS (US) 1997-08-06 — — EP claimed
EP-0606858-A1 Liquid crystal compositions and liquid crystal display devices CHISSO CORPORATION (JP) 1994-07-20 — — EP claimed
EP-0567207-A2 Method of reducing impurities in aqueous monomer solutions ROHM AND HAAS COMPANY (US) 1993-10-27 — — EP claimed
US-5208370-A Reducing protoanemonin by using phenylenediamines ROHM AND HAAS CO. (US) 1993-05-04 — — US claimed
US-4914213-A Indole derivatives and process for producing the same FUJI PHOTO FILM CO., LTD. (JP) 1990-04-03 — — US claimed
US-4870049-A TRANSFER SHEET FOR THERMAL PRINTING SHARP KABUSHIKI KAISHA (JP) 1989-09-26 — — US claimed
US-4707553-A Indole derivatives and process for producing the same FUJI PHOTO FILM CO., LTD. (JP) 1987-11-17 — — US claimed
US-4035144-A Dyeing preparations containing boric acid for preparing water-insoluble azo dyestuffs on fiber HOECHST AKTIENGESELLSCHAFT (DT) 1977-07-12 — — US claimed
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