SCHEMBL39057

SCHEMBL39057

COc1ccc(Nc2ccc(OC)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 1.00
RAB9A P51151 7/20 1.00
GAA P10253 5/20 1.00
NPC1 O15118 4/20 1.00
MAPK1 P28482 3/20 1.00
L3MBTL1 Q9Y468 2/20 1.00
KDM4E B2RXH2 2/20 1.00
THRB P10828 2/20 1.00
RECQL P46063 2/20 1.00
TDP1 Q9NUW8 2/20 1.00
NPSR1 Q6W5P4 1/20 1.00
NR4A1 P22736 1/20 0.77
ALDH1A1 P00352 4/20 0.67
HTT P42858 2/20 0.67
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
CA12 O43570 1/20 0.65
CA7 P43166 1/20 0.65
CA9 Q16790 1/20 0.65
CA14 Q9ULX7 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1459772 1.00 MAPT (1.00) MAPTRAB9AGAANPC1MAPK1
SCHEMBL12648780 0.92 MAPT (0.85) MAPTRAB9AGAANPC1MAPK1
SCHEMBL8943931 0.92 MAPT (0.85) MAPTRAB9AGAANPC1MAPK1
SCHEMBL7758813 0.92 RAB9A (0.85) MAPTRAB9AGAANPC1MAPK1
SCHEMBL1921511 0.92 MAPT (0.85) MAPTRAB9AGAANPC1MAPK1
SCHEMBL4427303 0.90 RAB9A (0.81) MAPTRAB9AGAANPC1MAPK1
SCHEMBL316390 0.90 RAB9A (0.81) MAPTRAB9AGAANPC1MAPK1
SCHEMBL20123327 0.90 MAPT (0.81) MAPTRAB9AGAANPC1MAPK1
SCHEMBL9479393 0.90 RAB9A (0.81) MAPTRAB9AGAANPC1MAPK1
SCHEMBL7256133 0.88 MAPT (0.77) MAPTRAB9AGAANPC1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4665 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080393-A Color-changing-stimulated polyimine ether ketone polymer and preparation method and application thereof 2026-05-26 CN claimed
WO-2026106183-A1 POLYCARBONATE RESIN COMPOSITION AND ARTICLE PRODUCED THEREFROM 롯데케미칼 주식회사 2026-05-21 WO claimed
EP-4357332-B1 COMPOUND, PREPARATION METHOD THEREFOR, USE THEREOF, AND PEROVSKITE SOLAR CELL COMPRISING SAME CONTEMPORARY AMPEREX TECHNOLOGY HONG KONG LTD (HK) 2026-04-22 EP claimed
US-12439765-B2 Compound, preparation method and use thereof and perovskite solar cell containing same CONTEMPORARY AMPEREX TECHNOLOGY (HONG KONG) LIMITED (CN) 2025-10-07 US claimed
CN-120117993-A Method for synthesizing hole transport material Spiro-OMeTAD by nickel-based catalyst catalysis 陕西师范大学 2025-06-10 CN claimed
CN-119977824-A Self-crosslinking compound and preparation method and application thereof 河南省柔性电子产业技术研究院 2025-05-13 CN claimed
CN-116444441-B Benzopyridazine compound and preparation method and application thereof 内蒙古大学 2025-04-29 CN claimed
US-20250110403-A1 PHOTOSENSITIVE COMPOSITION CONTAINING PFAS-FREE POLYCYCLOOLEFINIC POLYMERS AND SEMICONDUCTOR DEVICE MADE THEREOF PROMERUS, LLC (US) 2025-04-03 US claimed
US-20250110399-A1 PHOTOSENSITIVE COMPOSITION CONTAINING PFAS-FREE POLYCYCLOOLEFINIC TERPOLYMERS AND SEMICONDUCTOR DEVICE MADE THEREOF PROMERUS, LLC (US) 2025-04-03 US claimed
CN-119707791-A Double-response fluorescent probe for simultaneously imaging myelin and Abeta aggregates in AD brain, and preparation method and application thereof 南京师范大学 2025-03-28 CN claimed
EP-1379534-B1 RHODIUM AND IRIDIUM COMPLEXES COVION ORGANIC SEMICONDUCTORS (DE) 2004-12-15 EP claimed
US-20040133004-A1 Rhodium and iridium complexes MERCK PATENT GMBH (DE) 2004-07-08 US claimed
EP-0818526-B1 Stabilizers for the prevention of gum formation in gasoline CIBA SC HOLDING AG (CH) 2003-02-12 EP claimed
US-6410490-B1 OIL ADDITIVE MIXTURE CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-25 US claimed
US-5711767-A AMINES, PHENOLIC COMPOUNDS AND NITROXIDE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-01-27 US claimed
EP-0818526-A1 Stabilizers for the prevention of gum formation in gasoline Ciba SC Holding AG (CH) 1998-01-14 EP claimed
EP-0469889-B1 (p-Carbonylaminophenyl)-sulphonyl-nitromethane derivatives ZENECA LTD (GB) 1996-01-17 EP claimed
US-5189031-A Inhibitor of enzyme aldose reductase, useful in the treatment of certain peripheral effects of diabetes and galactosemia IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-02-23 US claimed
EP-0469889-A1 (p-Carbonylaminophenyl)-sulphonyl-nitromethane derivatives ZENECA LIMITED (GB) 1992-02-05 EP claimed
US-4001035-A COLORING COMPOSITION DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JA) 1977-01-04 US claimed