Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 6/20 | 0.74 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.48 |
| ▸ | KCNH3 known ✓ | Q9ULD8 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.96 |
| ▸ | MAPT | P10636 | 7/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.74 |
| ▸ | RAB9A | P51151 | 4/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | THRB | P10828 | 2/20 | 0.74 |
| ▸ | RECQL | P46063 | 2/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.74 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MMP14 | P50281 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1618639 | 0.98 | NR4A1 (1.00) | NR4A1MAPTALDH1A1GAATDP1 | |
| SCHEMBL27956260 | 0.92 | NR4A1 (0.88) | NR4A1MAPTALDH1A1GAATDP1 | |
| SCHEMBL11764736 | 0.90 | NR4A1 (0.85) | NR4A1MAPTALDH1A1GAATDP1 | |
| SCHEMBL30511913 | 0.87 | NR4A1 (0.79) | NR4A1MAPTALDH1A1GAATDP1 | |
| Sulfuric Acid SCHEMBL29722524 | 0.87 | NR4A1 (0.79) | NR4A1MAPTALDH1A1GAATDP1 | |
| Sulfuric Acid SCHEMBL11419340 | 0.87 | NR4A1 (0.79) | NR4A1MAPTALDH1A1GAATDP1 | |
| SCHEMBL1459772 | 0.86 | MAPT (1.00) | NR4A1MAPTALDH1A1GAATDP1 | |
| SCHEMBL39057 | 0.86 | MAPT (1.00) | NR4A1MAPTALDH1A1GAATDP1 | |
| Hydrochloric Acid SCHEMBL4376059 | 0.86 | ALDH1A1 (1.00) | NR4A1MAPTALDH1A1TDP1RAB9A | |
| Hydrochloric Acid SCHEMBL208637 | 0.86 | ALDH1A1 (1.00) | NR4A1MAPTALDH1A1TDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4511649-B1 | METHOD AND KIT FOR THE DETECTION OF CHROMIUM-6 IN A SAMPLE | SEEF B V (NL) | 2026-03-11 | — | — | EP | claimed |
| EP-4511649-A1 | METHOD FOR THE DETECTION OF CHROMIUM-6 IN A SAMPLE | SEEF B.V. (NL) | 2025-02-26 | — | — | EP | claimed |
| WO-2023219493-A1 | METHOD FOR THE DETECTION OF CHROMIUM-6 IN A SAMPLE | SEEF B.V. (NL) | 2023-11-16 | — | — | WO | claimed |
| JP-60181653-A | — | — | None | — | — | JP | disclosed |
| EP-4511649-B1 | METHOD AND KIT FOR THE DETECTION OF CHROMIUM-6 IN A SAMPLE | SEEF B V (NL) | 2026-03-11 | — | — | EP | disclosed |
| US-20250314593-A1 | DEVICES, METHODS AND KITS FOR DETECTING EXPLOSIVES AND ILLICIT DRUG SUBSTANCES | TRACE EYE-D, LLC | 2025-10-09 | — | — | US | disclosed |
| EP-4511649-A1 | METHOD FOR THE DETECTION OF CHROMIUM-6 IN A SAMPLE | SEEF B.V. (NL) | 2025-02-26 | — | — | EP | disclosed |
| WO-2023219493-A1 | METHOD FOR THE DETECTION OF CHROMIUM-6 IN A SAMPLE | SEEF B.V. (NL) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023150396-A1 | DEVICES, METHODS AND KITS FOR DETECTING EXPLOSIVES AND ILLICIT DRUG SUBSTANCES | TRACE EYE-D, LLC (US) | 2023-08-10 | — | — | WO | disclosed |
| US-20050042674-A9 | Common ligand mimics: thiazolidinediones and rhodanines | TRIAD THERAPEUTICS, INC. | 2005-02-24 | — | — | US | disclosed |
| EP-0884367-B1 | Light-writable data storage media containing cationic diphenylamine dyes | BAYER AG (DE) | 2003-08-13 | — | — | EP | disclosed |
| US-5952475-A | CATIONIC THIADIAZOLEDIPHENYLAMINE DYES FOR USE IN INKJET PRINTING AND IN LIGHT-WRITABLE DATA STORAGE MEDIA AND IN DYE TRANSFER FILMS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-09-14 | — | — | US | disclosed |
| US-5790627-A | Method and apparatus for observing a specimen using an X-ray microscope | RESEARCH DEVELOPMENT CORP. (JP) | 1998-08-04 | — | — | US | disclosed |
| EP-0567207-B1 | Method of reducing impurities in aqueous monomer solutions | ROHM & HAAS (US) | 1997-08-06 | — | — | EP | disclosed |
| EP-0763512-A1 | AIR BAG GAS GENERATING AGENT | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995011001-A1 | 1,3-PROPANDIONES FOR DYEING KERATINIC FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1995-04-27 | — | — | WO | disclosed |
| EP-0567207-A2 | Method of reducing impurities in aqueous monomer solutions | ROHM AND HAAS COMPANY (US) | 1993-10-27 | — | — | EP | disclosed |
| US-5208370-A | Reducing protoanemonin by using phenylenediamines | ROHM AND HAAS CO. (US) | 1993-05-04 | — | — | US | disclosed |
| JP-S60181653-A | OXYGEN DETECTOR | DAINIPPON PRINTING CO LTD | 1985-09-17 | — | — | JP | disclosed |
| US-4042329-A | Method and device for detecting cholesterol | BECTON, DICKINSON AND COMPANY (US) | 1977-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050042674-A9 | Common ligand mimics: thiazolidinediones and rhodanines | GPR65, NR2E3, FGFR3 | GAA 2005/4885CA2 1275/4885KCNH3 2998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.