SCHEMBL16186744

SCHEMBL16186744

CC(=O)OC1OC(C[18F])C(OC2OC3COC(c4ccccc4)OC3C(C)C2C)C(C)C1C

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.45
▸ KMT2A Q03164 2/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ TSHR P16473 1/20 0.34
▸ LMNA P02545 1/20 0.33
▸ ALDH1A1 P00352 3/20 0.32
▸ SELP P16109 1/20 0.32
▸ BCHE P06276 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL796260 0.91 TSHR (0.46) L3MBTL1KMT2AMEN1TSHRLMNA
SCHEMBL16186745 0.82 L3MBTL1 (0.37) L3MBTL1KMT2AMEN1TSHRLMNA
SCHEMBL25502843 0.81 L3MBTL1 (0.55) L3MBTL1KMT2AMEN1TSHRLMNA
SCHEMBL25502819 0.81 L3MBTL1 (0.55) L3MBTL1KMT2AMEN1TSHRLMNA
SCHEMBL19398465 0.80 L3MBTL1 (0.36) L3MBTL1KMT2AMEN1SELP
SCHEMBL15730317 0.78 L3MBTL1 (0.56) L3MBTL1KMT2AMEN1LMNAALDH1A1
SCHEMBL16189505 0.77 L3MBTL1 (0.48) L3MBTL1KMT2AMEN1TSHRLMNA
SCHEMBL7563649 0.77 L3MBTL1 (0.60) L3MBTL1KMT2AMEN1TSHRLMNA
SCHEMBL25503299 0.77 L3MBTL1 (0.60) L3MBTL1KMT2AMEN1TSHRLMNA
SCHEMBL25503494 0.77 L3MBTL1 (0.60) L3MBTL1KMT2AMEN1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9402925-B2 Probes and methods of imaging a bacterial infection THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO (US) 2016-08-02 — — US disclosed
US-20140314671-A1 PROBES AND METHODS OF IMAGING A BACTERIAL INFECTION THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2014-10-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140314671-A1 PROBES AND METHODS OF IMAGING A BACTERIAL INFECTION MPI, MGAM, TREH L3MBTL1 882/4885KMT2A 4520/4885MEN1 1869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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