Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17617256 | 0.94 | KMT2A (0.43) | MEN1KMT2AHDAC3HDAC1 | |
| SCHEMBL16187659 | 0.91 | MEN1 (0.47) | MEN1KMT2AHDAC3HDAC1 | |
| SCHEMBL16187431 | 0.91 | KMT2A (0.42) | MEN1KMT2ATLR7ADORA2AADORA1 | |
| SCHEMBL16187929 | 0.90 | KMT2A (0.39) | MEN1KMT2AHDAC3HDAC1 | |
| SCHEMBL17617257 | 0.88 | KMT2A (0.39) | MEN1KMT2A | |
| SCHEMBL16187457 | 0.88 | KMT2A (0.47) | MEN1KMT2ATLR7ADORA2AADORA1 | |
| SCHEMBL17617290 | 0.88 | KMT2A (0.41) | MEN1KMT2A | |
| SCHEMBL16187479 | 0.87 | KMT2A (0.43) | MEN1KMT2A | |
| SCHEMBL16187891 | 0.87 | SCN9A (0.42) | MEN1KMT2AHDAC3HDAC1KCNH2 | |
| SCHEMBL16187403 | 0.86 | KMT2A (0.47) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9808003-B2 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2017-11-07 | — | — | US | disclosed |
| US-9808003-B2 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2017-11-07 | — | — | US | disclosed |
| EP-2986593-B1 | HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS AND DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2017-07-19 | — | — | EP | disclosed |
| US-20160081334-A1 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2016-03-24 | — | — | US | disclosed |
| US-20160081334-A1 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2016-03-24 | — | — | US | disclosed |
| WO-2014170413-A1 | HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS AND DERIVATIVES THEREOF | SYNGENTA LIMITED (GB) | 2014-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160081334-A1 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | DDT, DHPS, HPD | MEN1 4465/4885KMT2A 1800/4885TLR7 4436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.