SCHEMBL16187759

SCHEMBL16187759

NCC(=O)N1CC[C@H](CO)[C@@H]1CO

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 2/20 0.42
▸ DPP8 Q6V1X1 2/20 0.42
▸ PREP P48147 1/20 0.42
▸ FAP Q12884 1/20 0.42
▸ DPP9 Q86TI2 1/20 0.42
▸ DPP7 Q9UHL4 2/20 0.35
▸ POLB P06746 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ CPN1 P15169 1/20 0.32
▸ CPB2 Q96IY4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14513315 0.81 CHRNB2 (0.34) DPP4POLBL3MBTL1
SCHEMBL11992501 0.81 DPP4 (0.42) DPP4DPP8PREPFAPDPP9
SCHEMBL1632383 0.68 — —
SCHEMBL1632385 0.68 — —
SCHEMBL15808498 0.68 POLB (0.66) DPP4DPP8PREPFAPDPP9
SCHEMBL19423712 0.68 POLB (0.66) DPP4DPP8PREPFAPDPP9
SCHEMBL1027107 0.68 POLB (0.66) DPP4DPP8PREPFAPDPP9
SCHEMBL18771558 0.67 DPP4 (0.39) DPP4DPP8PREPFAPDPP9
SCHEMBL21086475 0.67 DPP4 (0.39) DPP4DPP8PREPFAPDPP9
SCHEMBL18771492 0.67 DPP4 (0.39) DPP4DPP8PREPFAPDPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9394540-B2 Modified iRNA agents ALNYLAM PHARMACEUTICALS, INC. (US) 2016-07-19 — — US disclosed
US-20140316124-A1 MODIDIFED iRNA AGENTS BANK OF AMERICA, N.A. 2014-10-23 — — US disclosed
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