SCHEMBL16187995

SCHEMBL16187995

CCCCCCCOCC(O)C(O)CC

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 1/20 0.62
USP2 O75604 1/20 0.60
HTT P42858 2/20 0.58
MEN1 O00255 1/20 0.52
THRB P10828 1/20 0.52
KMT2A Q03164 1/20 0.52
MAPT P10636 1/20 0.52
LPAR5 Q9H1C0 4/20 0.50
LPAR1 Q92633 7/20 0.46
LPAR3 Q9UBY5 7/20 0.46
LPAR2 Q9HBW0 4/20 0.46
LPAR6 P43657 3/20 0.46
LPAR4 Q99677 3/20 0.46
PLA2G2C Q5R387 1/20 0.45
CES2 O00748 1/20 0.44
PRKD3 O94806 1/20 0.43
PRKCG P05129 1/20 0.43
PRKCB P05771 1/20 0.43
PRKCA P17252 1/20 0.43
PRKCH P24723 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1506142 1.00 SPHK1 (0.62) SPHK1USP2HTTMEN1THRB
SCHEMBL29169783 0.94 SPHK1 (0.69) SPHK1USP2HTTMEN1THRB
SCHEMBL7757196 0.91 SPHK1 (0.66) SPHK1USP2HTTMEN1THRB
SCHEMBL16187997 0.86 USP2 (0.69) SPHK1USP2HTTMEN1THRB
SCHEMBL9117099 0.86 SPHK1 (0.61) SPHK1USP2HTTMEN1THRB
SCHEMBL16187998 0.86 USP2 (0.69) SPHK1USP2HTTMEN1THRB
SCHEMBL14880189 0.86 SPHK1 (0.61) SPHK1USP2HTTMEN1THRB
SCHEMBL28128054 0.86 USP2 (0.69) SPHK1USP2HTTMEN1THRB
SCHEMBL29169743 0.85 SPHK1 (0.65) SPHK1USP2HTTMEN1THRB
SCHEMBL11302893 0.83 SPHK1 (0.58) SPHK1USP2HTTMEN1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9650321-B2 Renewable surfactants derived from sugar alcohols DOW GLOBAL TECHNOLOGIES LLC (US) 2017-05-16 US disclosed
US-20140316148-A1 Renewable Surfactants Derived from Sugar Alcohols DOW GLOBAL TECHNOLOGIES LLC (US) 2014-10-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140316148-A1 Renewable Surfactants Derived from Sugar Alcohols SORD, TREH, MGAM SPHK1 351/4885USP2 1147/4885HTT 714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.