Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 13/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16188984 | 0.92 | OPRM1 (0.54) | OPRM1OPRD1OPRK1LMNAPDE4D | |
| SCHEMBL16189005 | 0.90 | OPRM1 (0.49) | OPRM1OPRD1OPRK1LMNAPDE4D | |
| SCHEMBL16188985 | 0.90 | OPRM1 (0.52) | OPRM1OPRD1OPRK1LMNAPDE4D | |
| SCHEMBL16015642 | 0.86 | OPRM1 (0.71) | OPRM1OPRD1OPRK1LMNAPDE4D | |
| SCHEMBL17625331 | 0.85 | OPRM1 (0.49) | OPRM1OPRD1OPRK1LMNAPDE4D | |
| SCHEMBL16188983 | 0.82 | OPRM1 (0.52) | OPRM1OPRD1OPRK1LMNAPDE4D | |
| SCHEMBL17625328 | 0.78 | OPRM1 (0.73) | OPRM1OPRD1OPRK1LMNAPDE4D | |
| SCHEMBL16193375 | 0.78 | OPRM1 (0.52) | OPRM1OPRD1OPRK1PDE4DMRGPRX2 | |
| SCHEMBL12945147 | 0.78 | OPRM1 (0.73) | OPRM1OPRD1OPRK1LMNAPDE4D | |
| SCHEMBL12945202 | 0.77 | OPRM1 (0.58) | OPRM1OPRD1OPRK1LMNAPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014172478-A1 | COMPOUNDS FOR TREATMENT OF PAIN | VOLKMANN Robert | 2014-10-23 | — | — | WO | disclosed |