Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 16/20 | 0.73 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17625329 | 0.91 | OPRM1 (0.70) | OPRM1OPRK1OPRD1LMNAPDE4D | |
| SCHEMBL13100920 | 0.87 | OPRM1 (0.81) | OPRM1OPRK1OPRD1LMNAPDE4D | |
| SCHEMBL13534483 | 0.87 | OPRM1 (0.81) | OPRM1OPRK1OPRD1LMNAPDE4D | |
| SCHEMBL14852885 | 0.87 | OPRM1 (0.81) | OPRM1OPRK1OPRD1LMNAPDE4D | |
| SCHEMBL16188984 | 0.86 | OPRM1 (0.54) | OPRM1OPRK1OPRD1LMNAPDE4D | |
| SCHEMBL12948089 | 0.85 | OPRM1 (1.00) | OPRM1OPRK1OPRD1LMNAPDE4D | |
| SCHEMBL16189013 | 0.78 | OPRM1 (0.53) | OPRM1OPRK1OPRD1LMNAPDE4D | |
| SCHEMBL20170773 | 0.78 | OPRM1 (0.66) | OPRM1OPRK1OPRD1LMNAPDE4D | |
| SCHEMBL16188985 | 0.78 | OPRM1 (0.52) | OPRM1OPRK1OPRD1LMNAPDE4D | |
| SCHEMBL18878785 | 0.77 | OPRM1 (0.65) | OPRM1OPRK1OPRD1LMNAPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160083393-A1 | COMPOUNDS FOR TREATMENT OF PAIN | BIOPHARMA WORKS | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160083393-A1 | COMPOUNDS FOR TREATMENT OF PAIN | OPRK1, OPRL1, OPRD1 | OPRM1 4/4885OPRK1 1/4885OPRD1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.