SCHEMBL16189080

SCHEMBL16189080

Cc1cc(C)nc(-c2ccc(-c3cc(-c4ccc(-c5ccccc5)cc4)cc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)c3)cc2)n1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.59
▸ L3MBTL1 Q9Y468 2/20 0.55
▸ ABCG2 Q9UNQ0 7/20 0.53
▸ KMT2A Q03164 4/20 0.53
▸ MAPT P10636 4/20 0.53
▸ MEN1 O00255 3/20 0.53
▸ MAPK1 P28482 2/20 0.53
▸ HPGD P15428 2/20 0.53
▸ CYP1A2 P05177 1/20 0.53
▸ CYP2C9 P11712 1/20 0.53
▸ CYP2C19 P33261 1/20 0.53
▸ ATM Q13315 1/20 0.53
▸ NPC1 O15118 1/20 0.49
▸ GBA1 P04062 1/20 0.49
▸ RAB9A P51151 1/20 0.49
▸ TSHR P16473 2/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ HSD17B10 Q99714 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17511962 1.00 LMNA (0.59) LMNAL3MBTL1ABCG2KMT2AMAPT
SCHEMBL16189469 1.00 LMNA (0.59) LMNAL3MBTL1ABCG2KMT2AMAPT
SCHEMBL16189209 1.00 LMNA (0.59) LMNAL3MBTL1ABCG2KMT2AMAPT
SCHEMBL17511881 1.00 LMNA (0.59) LMNAL3MBTL1ABCG2KMT2AMAPT
SCHEMBL16189465 0.95 LMNA (0.54) LMNAL3MBTL1ABCG2KMT2AMAPT
SCHEMBL17511924 0.94 LMNA (0.66) LMNAL3MBTL1ABCG2KMT2AMAPT
SCHEMBL17511922 0.94 LMNA (0.66) LMNAL3MBTL1ABCG2KMT2AMAPT
SCHEMBL17511846 0.94 LMNA (0.66) LMNAL3MBTL1ABCG2KMT2AMAPT
SCHEMBL17932802 0.94 LMNA (0.66) LMNAL3MBTL1ABCG2KMT2AMAPT
SCHEMBL16189220 0.94 LMNA (0.66) LMNAL3MBTL1ABCG2KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11329231-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2022-05-10 — — US disclosed
US-20200058878-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-20 — — US disclosed
US-9780310-B2 Heterocyclic compound for organic electroluminescent device and its application TOSOH CORPORATION (JP) 2017-10-03 — — US disclosed
US-9780310-B2 Heterocyclic compound for organic electroluminescent device and its application TOSOH CORPORATION (JP) 2017-10-03 — — US disclosed
US-20170186964-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-29 — — US disclosed
US-20170186964-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-29 — — US disclosed
EP-3048654-A2 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2016-07-27 — — EP disclosed
US-20160211454-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-21 — — US disclosed
US-20160211454-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-21 — — US disclosed
US-20160056388-A1 HETEROCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ITS APPLICATION TOSOH CORPORATION (JP) 2016-02-25 — — US disclosed
US-20160056388-A1 HETEROCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ITS APPLICATION TOSOH CORPORATION (JP) 2016-02-25 — — US disclosed
WO-2014171541-A1 HETEROCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE ELEMENT AND APPLICATION THEREFOR 東ソー株式会社 (JP) 2014-10-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160056388-A1 HETEROCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ITS APPLICATION AOC2, AZI2, KCNH2 LMNA 2238/4885L3MBTL1 997/4885ABCG2 544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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