SCHEMBL16189166

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16189037	0.95	WNT3A (0.47)	WNT3ADYRK1APORCNALDH1A1MAPT
	SCHEMBL16189185	0.91	WNT3A (0.46)	WNT3ADYRK1APORCNALDH1A1MAPT
	SCHEMBL16189174	0.91	MAPT (0.44)	ALDH1A1MAPTHPGDKDM4ELMNA
	SCHEMBL19543720	0.89	DYRK1A (0.46)	WNT3ADYRK1APORCNALDH1A1MAPT
	SCHEMBL9958189	0.87	MEN1 (0.51)	ALDH1A1MAPTHPGDKDM4ELMNA
	SCHEMBL18086796	0.87	MEN1 (0.51)	ALDH1A1MAPTHPGDKDM4ELMNA
	SCHEMBL16189049	0.87	CYP1A1 (0.48)	WNT3ADYRK1APORCNALDH1A1MAPT
	SCHEMBL16189186	0.86	WNT3A (0.41)	WNT3ADYRK1APORCNALDH1A1MAPT
	SCHEMBL16189177	0.86	WNT3A (0.50)	WNT3APORCN
	SCHEMBL16305222	0.86	MEN1 (0.49)	ALDH1A1MAPTHPGDKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.