Sugi Predict

Sugi Predict / Compounds / SCHEMBL16189290

SCHEMBL16189290

SCHEMBL16189290

Cc1cc(C)nc(-c2cccc(-c3cc(-c4nc(-c5ccccc5)cc(-c5ccccc5)n4)cc(-c4cc5cccc6ccc7cccc4c7c65)c3)c2)n1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 6/20 0.38
▸ KMT2A Q03164 6/20 0.38
▸ MAPT P10636 5/20 0.38
▸ HPGD P15428 5/20 0.38
▸ ALDH1A1 P00352 4/20 0.38
▸ LMNA P02545 3/20 0.38
▸ KDM4E B2RXH2 3/20 0.38
▸ CYP1A2 P05177 2/20 0.35
▸ ERBB2 P04626 1/20 0.35
▸ FYN P06241 1/20 0.35
▸ MAOA P21397 1/20 0.35
▸ ACHE P22303 1/20 0.35
▸ AHR P35869 1/20 0.35
▸ NTSR1 P30989 1/20 0.34
▸ ACACA Q13085 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ GLA P06280 1/20 0.33
▸ ABCG2 Q9UNQ0 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16189391 0.96 LMNA (0.38) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL16189193 0.94 MEN1 (0.39) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL16189389 0.94 MEN1 (0.39) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL16189312 0.94 MEN1 (0.37) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL16189342 0.93 LMNA (0.40) MEN1KMT2AMAPTHPGDLMNA
SCHEMBL16189167 0.91 MEN1 (0.37) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL16189326 0.90 KDM4E (0.34) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL16189313 0.90 KMT2A (0.37) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL16189421 0.89 LMNA (0.43) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL16189374 0.89 MEN1 (0.36) MEN1KMT2AMAPTHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9780310-B2 Heterocyclic compound for organic electroluminescent device and its application TOSOH CORPORATION (JP) 2017-10-03 — — US disclosed
US-9780310-B2 Heterocyclic compound for organic electroluminescent device and its application TOSOH CORPORATION (JP) 2017-10-03 — — US disclosed
US-20160056388-A1 HETEROCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ITS APPLICATION TOSOH CORPORATION (JP) 2016-02-25 — — US disclosed
US-20160056388-A1 HETEROCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ITS APPLICATION TOSOH CORPORATION (JP) 2016-02-25 — — US disclosed
WO-2014171541-A1 HETEROCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE ELEMENT AND APPLICATION THEREFOR 東ソー株式会社 (JP) 2014-10-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160056388-A1 HETEROCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ITS APPLICATION AOC2, AZI2, KCNH2 MEN1 2195/4885KMT2A 1481/4885MAPT 4371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.